μ-Opioid Receptors: Correlation of Agonist Efficacy for Signalling with Ability to Activate Internalization

We have compared the ability of a number of μ-opioid receptor (MOPr) ligands to activate G proteins with their abilities to induce MOPr phosphorylation, to promote association of arrestin-3 and to cause MOPr internalization. For a model of G protein-coupled receptor (GPCR) activation where all agoni...

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Main Authors: McPherson, Jamie, Rivero, Guadalupe, Baptist, Myma, Llorente, Javier, Al-Sabah, Suleiman, Krasel, Cornelius, Dewey, William L., Bailey, Chris P., Rosethorne, Elizabeth M., Charlton, Steven J., Henderson, Graeme, Kelly, Eamonn
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Pharmacology and Experimental Therapeutics 2010
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2981392/
https://ncbi.nlm.nih.gov/pubmed/20647394
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/mol.110.066613
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