ACTIVATION AND INTERNALIZATION OF THE μ-OPIOID RECEPTOR BY THE NEWLY DISCOVERED ENDOGENOUS AGONISTS, ENDOMORPHIN-1 AND ENDOMORPHIN-2

The multiple effects of opiate alkaloids, important therapeutic drugs used for pain control, are mediated by the neuronal μ-opioid receptor. Among the side effects of these drugs is a profound impairment of gastrointestinal transit. Endomorphins are opioid peptides recently isolated from the nervous...

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Bibliographic Details
Published in:Neuroscience
Main Authors: McCONALOGUE, K., GRADY, E. F., MINNIS, J., BALESTRA, B., TONINI, M., BRECHA, N. C., BUNNETT, N. W., STERNINI, C.
Format: Artigo
Language:Inglês
Published: 1999
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4472477/
https://ncbi.nlm.nih.gov/pubmed/10218804
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