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Contribution of Endogenous Spinal Endomorphin 2 to Intrathecal Opioid Antinociception in Rats Is Agonist-Dependent and Sexually Dimorphic

Interactions between exogenous and endogenous opioids are not commonly investigated as a basis for sexually dimorphic opioid analgesia. We investigated the influence of spinal endomorphin 2 (EM2), an endogenous mu-opioid receptor (MOR) ligand, on the spinal antinociception produced by intrathecally...

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Bibliografische gegevens
Gepubliceerd in:J Pain
Hoofdauteurs: Kumar, Arjun, Liu, Nai-Jiang, Madia, Priyanka A., Gintzler, Alan R.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2015
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5087106/
https://ncbi.nlm.nih.gov/pubmed/26342648
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jpain.2015.08.003
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