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Spinal Endomorphin 2 Antinociception and the Mechanisms That Produce It Are Both Sex- and Stage of Estrus Cycle–Dependent in Rats

Endomorphin 2 (EM2) is the predominant endogenous mu-opioid receptor (MOR) ligand in the spinal cord. Given its endogenous presence, antinociceptive responsiveness to the intrathecal application of EM2 most likely reflects its ability to modulate nociception when released in situ. In order to explor...

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Detalhes bibliográficos
Main Authors: Liu, Nai-Jiang, Gintzler, Alan R.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3980941/
https://ncbi.nlm.nih.gov/pubmed/24084000
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jpain.2013.09.002
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