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Agonist-selective endocytosis of mu opioid receptor by neurons in vivo.

Opiate alkaloids are potent analgesics that exert multiple pharmacological effects in the nervous system by activating G protein-coupled receptors. Receptor internalization upon stimulation may be important for desensitization and resensitization, which affect cellular responsiveness to ligands. Her...

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Udgivet i:Proc Natl Acad Sci U S A
Principais autores: Sternini, C, Spann, M, Anton, B, Keith, D E, Bunnett, N W, von Zastrow, M, Evans, C, Brecha, N C
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 1996
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC38626/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8799185/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.93.17.9241
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