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Agonist-selective endocytosis of mu opioid receptor by neurons in vivo.

Opiate alkaloids are potent analgesics that exert multiple pharmacological effects in the nervous system by activating G protein-coupled receptors. Receptor internalization upon stimulation may be important for desensitization and resensitization, which affect cellular responsiveness to ligands. Her...

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Autors principals: Sternini, C, Spann, M, Anton, B, Keith, D E, Bunnett, N W, von Zastrow, M, Evans, C, Brecha, N C
Format: Artigo
Idioma:Inglês
Publicat: 1996
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC38626/
https://ncbi.nlm.nih.gov/pubmed/8799185
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