Thioredoxin Inhibitors Attenuate Platelet Function and Thrombus Formation

Thioredoxin (Trx) is an oxidoreductase with important physiological function. Imbalances in the NADPH/thioredoxin reductase/thioredoxin system are associated with a number of pathologies, particularly cancer, and a number of clinical trials for thioredoxin and thioredoxin reductase inhibitors have b...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Metcalfe, Clive, Ramasubramoni, Anjana, Pula, Giordano, Harper, Matthew T., Mundell, Stuart J., Coxon, Carmen H.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2016
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5055343/
https://ncbi.nlm.nih.gov/pubmed/27716777
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0163006
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