RhoG Protein Regulates Platelet Granule Secretion and Thrombus Formation in Mice

Rho GTPases such as Rac, RhoA, and Cdc42 are vital for normal platelet function, but the role of RhoG in platelets has not been studied. In other cells, RhoG orchestrates processes integral to platelet function, including actin cytoskeletal rearrangement and membrane trafficking. We therefore hypoth...

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Hlavní autoři: Goggs, Robert, Harper, Matthew T., Pope, Robert J., Savage, Joshua S., Williams, Christopher M., Mundell, Stuart J., Heesom, Kate J., Bass, Mark, Mellor, Harry, Poole, Alastair W.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Biochemistry and Molecular Biology 2013
Témata:
Cell Biology
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3837162/
https://ncbi.nlm.nih.gov/pubmed/24106270
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.504100
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