RhoG Protein Regulates Platelet Granule Secretion and Thrombus Formation in Mice

Rho GTPases such as Rac, RhoA, and Cdc42 are vital for normal platelet function, but the role of RhoG in platelets has not been studied. In other cells, RhoG orchestrates processes integral to platelet function, including actin cytoskeletal rearrangement and membrane trafficking. We therefore hypoth...

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Main Authors: Goggs, Robert, Harper, Matthew T., Pope, Robert J., Savage, Joshua S., Williams, Christopher M., Mundell, Stuart J., Heesom, Kate J., Bass, Mark, Mellor, Harry, Poole, Alastair W.
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Biochemistry and Molecular Biology 2013
Assuntos:
Cell Biology
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3837162/
https://ncbi.nlm.nih.gov/pubmed/24106270
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.504100
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