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Arrestin Scaffolds NHERF1 to the P2Y(12) Receptor to Regulate Receptor Internalization
We have recently shown in a patient with mild bleeding that the PDZ-binding motif of the platelet G protein-coupled P2Y(12) receptor (P2Y(12)R) is required for effective receptor traffic in human platelets. In this study we show for the first time that the PDZ motif-binding protein NHERF1 exerts a m...
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| Autors principals: | , , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
American Society for Biochemistry and Molecular Biology
2012
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3397875/ https://ncbi.nlm.nih.gov/pubmed/22610101 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.347104 |
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