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Deletion of the distal COOH-terminus of the A(2B) adenosine receptor switches internalization to an arrestin- and clathrin-independent pathway and inhibits recycling

BACKGROUND AND PURPOSE: We have investigated the effect of deletions of a postsynaptic density, disc large and zo-1 protein (PDZ) motif at the end of the COOH-terminus of the rat A(2B) adenosine receptor on intracellular trafficking following long-term exposure to the agonist 5′-(N-ethylcarboxamido)...

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Detalhes bibliográficos
Main Authors: Mundell, SJ, Matharu, A-L, Nisar, S, Palmer, TM, Benovic, JL, Kelly, E
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Publishing Ltd 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2828017/
https://ncbi.nlm.nih.gov/pubmed/20128803
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1476-5381.2009.00598.x
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