Monoglyceride lipase: structure and inhibitors

Autor Scalvini, Laura, Piomelli, Daniele, Mor, Marco
Vydáno v Chem Phys Lipids (2015)

Melatonin Receptor Agonists: New Options for Insomnia and Depression Treatment

Autor Spadoni, Gilberto, Bedini, Annalida, Rivara, Silvia, Mor, Marco
Vydáno v CNS Neurosci Ther (2010)

Different roles for the acyl chain and the amine leaving group in the substrate selectivity of N-Acylethanolamine acid amidase

Autor Ghidini, Andrea, Scalvini, Laura, Palese, Francesca, Lodola, Alessio, Mor, Marco, Piomelli, Daniele
Vydáno v J Enzyme Inhib Med Chem (2021)

Quantum mechanics/molecular mechanics modeling of fatty acid amide hydrolase reactivation distinguishes substrate from irreversible covalent inhibitors

Autor Lodola, Alessio, Capoferri, Luigi, Rivara, Silvia, Tarzia, Giorgio, Piomelli, Daniele, Mulholland, Adrian, Mor, Marco
Vydáno 2013

Predicting the Reactivity of Nitrile-Carrying Compounds with Cysteine: A Combined Computational and Experimental Study

Autor Berteotti, Anna, Vacondio, Federica, Lodola, Alessio, Bassi, Michele, Silva, Claudia, Mor, Marco, Cavalli, Andrea
Vydáno 2014

A Catalytic Mechanism for Cysteine N-Terminal Nucleophile Hydrolases, as Revealed by Free Energy Simulations

Autor Lodola, Alessio, Branduardi, Davide, De Vivo, Marco, Capoferri, Luigi, Mor, Marco, Piomelli, Daniele, Cavalli, Andrea
Vydáno 2012

Kinetic analysis and molecular modeling of the inhibition mechanism of roneparstat (SST0001) on human heparanase

Autor Pala, Daniele, Rivara, Silvia, Mor, Marco, Milazzo, Ferdinando Maria, Roscilli, Giuseppe, Pavoni, Emiliano, Giannini, Giuseppe
Vydáno v Glycobiology (2016)

Conformational Effects in Enzyme Catalysis: Reaction via a High Energy Conformation in Fatty Acid Amide Hydrolase

Autor Lodola, Alessio, Mor, Marco, Zurek, Jolanta, Tarzia, Giorgio, Piomelli, Daniele, Harvey, Jeremy N., Mulholland, Adrian J.
Vydáno 2007

Comparative Analysis of Virtual Screening Approaches in the Search for Novel EphA2 Receptor Antagonists

Autor Callegari, Donatella, Pala, Daniele, Scalvini, Laura, Tognolini, Massimiliano, Incerti, Matteo, Rivara, Silvia, Mor, Marco, Lodola, Alessio
Vydáno v Molecules (2015)

Covalent inhibitors of fatty acid amide hydrolase (FAAH): A rationale for the activity of piperidine and piperazine aryl ureas

Autor Palermo, Giulia, Branduardi, Davide, Masetti, Matteo, Lodola, Alessio, Mor, Marco, Piomelli, Daniele, Cavalli, Andrea, De Vivo, Marco
Vydáno 2011

Free-energy studies reveal a possible mechanism for oxidation-dependent inhibition of MGL

Autor Scalvini, Laura, Vacondio, Federica, Bassi, Michele, Pala, Daniele, Lodola, Alessio, Rivara, Silvia, Jung, Kwang-Mook, Piomelli, Daniele, Mor, Marco
Vydáno v Sci Rep (2016)

Low molecular weight heparins in COVID-19 patients: beware of augmented renal clearance!

Autor Tomasa-Irriguible, Teresa Maria, Martínez-Vega, Sergi, Mor-Marco, Ester, Herraiz-Ruiz, Alba, Raguer-Pardo, Laura, Cubells-Larrosa, Carlos
Vydáno v Crit Care (2020)

Synthesis and Structure–Activity Relationships of N-(2-Oxo-3-oxetanyl)amides as N-Acylethanolamine-hydrolyzing Acid Amidase Inhibitors

Autor Solorzano, Carlos, Antonietti, Francesca, Duranti, Andrea, Tontini, Andrea, Rivara, Silvia, Lodola, Alessio, Vacondio, Federica, Tarzia, Giorgio, Piomelli, Daniele, Mor, Marco
Vydáno 2010

3–Aminoazetidin–2–one Derivatives as N–Acylethanolamine Acid Amidase (NAAA) Inhibitors Suitable for Systemic Administration

Autor Fiasella, Annalisa, Nuzzi, Andrea, Summa, Maria, Armirotti, Andrea, Tarozzo, Glauco, Tarzia, Giorgio, Mor, Marco, Bertozzi, Fabio, Bandiera, Tiziano, Piomelli, Daniele
Vydáno v ChemMedChem (2014)

Peroxide-dependent MGL sulfenylation regulates 2-AG-mediated endocannabinoid signaling in brain neurons

Autor Dotsey, Emmanuel Y., Jung, Kwang-Mook, Basit, Abdul, Wei, Don, Daglian, Jennifer, Vacondio, Federica, Armirotti, Andrea, Mor, Marco, Piomelli, Daniele
Vydáno v Chem Biol (2015)

Discovery of Potent and Reversible Monoacylglycerol Lipase Inhibitors

Autor King, Alvin R., Dotsey, Emmanuel Y., Lodola, Alessio, Jung, Kwang Mook, Ghomian, Azar, Qiu, Yan, Fu, Jin, Mor, Marco, Piomelli, Daniele
Vydáno 2009

Synthesis and characterization of a peripherally restricted CB(1) cannabinoid antagonist, URB447, that reduces feeding and body-weight gain in mice

Autor LoVerme, Jesse, Duranti, Andrea, Tontini, Andrea, Spadoni, Gilberto, Mor, Marco, Rivara, Silvia, Stella, Nephi, Xu, Cong, Tarzia, Giorgio, Piomelli, Daniele
Vydáno 2008

Cardioprotective effects of fatty acid amide hydrolase inhibitor URB694, in a rodent model of trait anxiety

Autor Carnevali, Luca, Vacondio, Federica, Rossi, Stefano, Macchi, Emilio, Spadoni, Gilberto, Bedini, Annalida, Neumann, Inga D., Rivara, Silvia, Mor, Marco, Sgoifo, Andrea
Vydáno v Sci Rep (2015)

Chiral Recognition of Flexible Melatonin Receptor Ligands Induced by Conformational Equilibria

Autor Elisi, Gian Marco, Bedini, Annalida, Scalvini, Laura, Carmi, Caterina, Bartolucci, Silvia, Lucini, Valeria, Scaglione, Francesco, Mor, Marco, Rivara, Silvia, Spadoni, Gilberto
Vydáno v Molecules (2020)

A second generation of carbamate-based fatty acid amide hydrolase inhibitors with improved activity in vivo

Autor Clapper, Jason R., Vacondio, Federica, King, Alvin R., Duranti, Andrea, Tontini, Andrea, Silva, Claudia, Sanchini, Silvano, Tarzia, Giorgio, Mor, Marco, Piomelli, Daniele
Vydáno 2009