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Covalent inhibitors of fatty acid amide hydrolase (FAAH): A rationale for the activity of piperidine and piperazine aryl ureas

Recently, covalent drugs have attracted great interest in the drug discovery community, with successful examples that have demonstrated their therapeutic effects. Here, we focus on the covalent inhibition of the fatty acid amide hydrolase (FAAH), which is a promising strategy in the treatment of pai...

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書誌詳細
主要な著者: Palermo, Giulia, Branduardi, Davide, Masetti, Matteo, Lodola, Alessio, Mor, Marco, Piomelli, Daniele, Cavalli, Andrea, De Vivo, Marco
フォーマット: Artigo
言語:Inglês
出版事項: 2011
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3774108/
https://ncbi.nlm.nih.gov/pubmed/21830831
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jm2004283
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