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Covalent inhibitors of fatty acid amide hydrolase (FAAH): A rationale for the activity of piperidine and piperazine aryl ureas

Recently, covalent drugs have attracted great interest in the drug discovery community, with successful examples that have demonstrated their therapeutic effects. Here, we focus on the covalent inhibition of the fatty acid amide hydrolase (FAAH), which is a promising strategy in the treatment of pai...

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Библиографические подробности
Главные авторы: Palermo, Giulia, Branduardi, Davide, Masetti, Matteo, Lodola, Alessio, Mor, Marco, Piomelli, Daniele, Cavalli, Andrea, De Vivo, Marco
Формат: Artigo
Язык:Inglês
Опубликовано: 2011
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3774108/
https://ncbi.nlm.nih.gov/pubmed/21830831
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jm2004283
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