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Covalent inhibitors of fatty acid amide hydrolase (FAAH): A rationale for the activity of piperidine and piperazine aryl ureas

Recently, covalent drugs have attracted great interest in the drug discovery community, with successful examples that have demonstrated their therapeutic effects. Here, we focus on the covalent inhibition of the fatty acid amide hydrolase (FAAH), which is a promising strategy in the treatment of pai...

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Main Authors: Palermo, Giulia, Branduardi, Davide, Masetti, Matteo, Lodola, Alessio, Mor, Marco, Piomelli, Daniele, Cavalli, Andrea, De Vivo, Marco
Formato: Artigo
Idioma:Inglês
Publicado: 2011
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3774108/
https://ncbi.nlm.nih.gov/pubmed/21830831
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jm2004283
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