On the Use of 2,5-Dimethyl-Pyrrol-1-yl-Benzoic Acid Derivatives as EPH-Ephrin Antagonists

af Lodola, Alessio, Incerti, Matteo, Tognolini, Massimiliano
Udgivet 2014

Theoretical Model of EphA2-Ephrin A1 Inhibition

af Jedwabny, Wiktoria, Lodola, Alessio, Dyguda-Kazimierowicz, Edyta
Udgivet i Molecules (2018)

Homology Models of Melatonin Receptors: Challenges and Recent Advances

af Pala, Daniele, Lodola, Alessio, Bedini, Annalida, Spadoni, Gilberto, Rivara, Silvia
Udgivet 2013

Different roles for the acyl chain and the amine leaving group in the substrate selectivity of N-Acylethanolamine acid amidase

af Ghidini, Andrea, Scalvini, Laura, Palese, Francesca, Lodola, Alessio, Mor, Marco, Piomelli, Daniele
Udgivet i J Enzyme Inhib Med Chem (2021)

Quantum mechanics/molecular mechanics modeling of fatty acid amide hydrolase reactivation distinguishes substrate from irreversible covalent inhibitors

af Lodola, Alessio, Capoferri, Luigi, Rivara, Silvia, Tarzia, Giorgio, Piomelli, Daniele, Mulholland, Adrian, Mor, Marco
Udgivet 2013

Predicting the Reactivity of Nitrile-Carrying Compounds with Cysteine: A Combined Computational and Experimental Study

af Berteotti, Anna, Vacondio, Federica, Lodola, Alessio, Bassi, Michele, Silva, Claudia, Mor, Marco, Cavalli, Andrea
Udgivet 2014

Mechanistic Insights into the Reaction of Chlorination of Tryptophan Catalyzed by Tryptophan 7-Halogenase

af Karabencheva-Christova, Tatyana G., Torras, Juan, Mulholland, Adrian J., Lodola, Alessio, Christov, Christo Z.
Udgivet i Sci Rep (2017)

Lithocholic Acid Is an Eph-ephrin Ligand Interfering with Eph-kinase Activation

af Giorgio, Carmine, Hassan Mohamed, Iftiin, Flammini, Lisa, Barocelli, Elisabetta, Incerti, Matteo, Lodola, Alessio, Tognolini, Massimiliano
Udgivet 2011

A Catalytic Mechanism for Cysteine N-Terminal Nucleophile Hydrolases, as Revealed by Free Energy Simulations

af Lodola, Alessio, Branduardi, Davide, De Vivo, Marco, Capoferri, Luigi, Mor, Marco, Piomelli, Daniele, Cavalli, Andrea
Udgivet 2012

Conformational Effects in Enzyme Catalysis: Reaction via a High Energy Conformation in Fatty Acid Amide Hydrolase

af Lodola, Alessio, Mor, Marco, Zurek, Jolanta, Tarzia, Giorgio, Piomelli, Daniele, Harvey, Jeremy N., Mulholland, Adrian J.
Udgivet 2007

Comparative Analysis of Virtual Screening Approaches in the Search for Novel EphA2 Receptor Antagonists

af Callegari, Donatella, Pala, Daniele, Scalvini, Laura, Tognolini, Massimiliano, Incerti, Matteo, Rivara, Silvia, Mor, Marco, Lodola, Alessio
Udgivet i Molecules (2015)

Covalent inhibitors of fatty acid amide hydrolase (FAAH): A rationale for the activity of piperidine and piperazine aryl ureas

af Palermo, Giulia, Branduardi, Davide, Masetti, Matteo, Lodola, Alessio, Mor, Marco, Piomelli, Daniele, Cavalli, Andrea, De Vivo, Marco
Udgivet 2011

Conformational Effects on the pro-S Hydrogen Abstraction Reaction in Cyclooxygenase-1: An Integrated QM/MM and MD Study

af Christov, Christo Z., Lodola, Alessio, Karabencheva-Christova, Tatyana G., Wan, Shunzhou, Coveney, Peter V., Mulholland, Adrian J.
Udgivet 2013

Mechanism of inhibition of SARS-CoV-2 M(pro) by N3 peptidyl Michael acceptor explained by QM/MM simulations and design of new derivatives with tunable chemical reactivity

af Arafet, Kemel, Serrano-Aparicio, Natalia, Lodola, Alessio, Mulholland, Adrian J., González, Florenci V., Świderek, Katarzyna, Moliner, Vicent
Udgivet i Chem Sci (2020)

Free-energy studies reveal a possible mechanism for oxidation-dependent inhibition of MGL

af Scalvini, Laura, Vacondio, Federica, Bassi, Michele, Pala, Daniele, Lodola, Alessio, Rivara, Silvia, Jung, Kwang-Mook, Piomelli, Daniele, Mor, Marco
Udgivet i Sci Rep (2016)

Synthesis and Structure–Activity Relationships of N-(2-Oxo-3-oxetanyl)amides as N-Acylethanolamine-hydrolyzing Acid Amidase Inhibitors

af Solorzano, Carlos, Antonietti, Francesca, Duranti, Andrea, Tontini, Andrea, Rivara, Silvia, Lodola, Alessio, Vacondio, Federica, Tarzia, Giorgio, Piomelli, Daniele, Mor, Marco
Udgivet 2010

Discovery of Potent and Reversible Monoacylglycerol Lipase Inhibitors

af King, Alvin R., Dotsey, Emmanuel Y., Lodola, Alessio, Jung, Kwang Mook, Ghomian, Azar, Qiu, Yan, Fu, Jin, Mor, Marco, Piomelli, Daniele
Udgivet 2009

Evaluation of the Anti-Tumor Activity of Small Molecules Targeting Eph/Ephrins in APC (min)/J Mice

af Corrado, Miriam, Giorgio, Carmine, Barocelli, Elisabetta, Marzetti, Giuseppe Vittucci, Cantoni, Anna Maria, Di Lecce, Rosanna, Incerti, Matteo, Castelli, Riccardo, Lodola, Alessio, Tognolini, Massimiliano
Udgivet i Pharmaceuticals (Basel) (2020)

UniPR1331: Small Eph/Ephrin Antagonist Beneficial in Intestinal Inflammation by Interfering with Type-B Signaling

af Giorgio, Carmine, Allodi, Marika, Palese, Simone, Grandi, Andrea, Tognolini, Massimiliano, Castelli, Riccardo, Lodola, Alessio, Flammini, Lisa, Cantoni, Anna Maria, Barocelli, Elisabetta, Bertoni, Simona
Udgivet i Pharmaceuticals (Basel) (2021)

Structure-property relationships of a class of carbamate-based Fatty Acid Amide Hydrolase (FAAH) inhibitors: chemical and biological stability

af Vacondio, Federica, Silva, Claudia, Lodola, Alessio, Fioni, Alessandro, Rivara, Silvia, Duranti, Andrea, Tontini, Andrea, Sanchini, Silvano, Clapper, Jason, Piomelli, Daniele, Mor, Marco, Tarzia, Giorgio
Udgivet 2009