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Comparative Analysis of Virtual Screening Approaches in the Search for Novel EphA2 Receptor Antagonists
The EphA2 receptor and its ephrin-A1 ligand form a key cell communication system, which has been found overexpressed in many cancer types and involved in tumor growth. Recent medicinal chemistry efforts have identified bile acid derivatives as low micromolar binders of the EphA2 receptor. However, t...
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| 出版年: | Molecules |
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| 主要な著者: | , , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
MDPI
2015
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6331951/ https://ncbi.nlm.nih.gov/pubmed/26393553 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules200917132 |
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