Comparative Analysis of Virtual Screening Approaches in the Search for Novel EphA2 Receptor Antagonists

The EphA2 receptor and its ephrin-A1 ligand form a key cell communication system, which has been found overexpressed in many cancer types and involved in tumor growth. Recent medicinal chemistry efforts have identified bile acid derivatives as low micromolar binders of the EphA2 receptor. However, t...

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Detaylı Bibliyografya
Yayımlandı:Molecules
Asıl Yazarlar: Callegari, Donatella, Pala, Daniele, Scalvini, Laura, Tognolini, Massimiliano, Incerti, Matteo, Rivara, Silvia, Mor, Marco, Lodola, Alessio
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: MDPI 2015
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC6331951/
https://ncbi.nlm.nih.gov/pubmed/26393553
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules200917132
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