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Comparative Analysis of Virtual Screening Approaches in the Search for Novel EphA2 Receptor Antagonists

The EphA2 receptor and its ephrin-A1 ligand form a key cell communication system, which has been found overexpressed in many cancer types and involved in tumor growth. Recent medicinal chemistry efforts have identified bile acid derivatives as low micromolar binders of the EphA2 receptor. However, t...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Molecules
Prif Awduron: Callegari, Donatella, Pala, Daniele, Scalvini, Laura, Tognolini, Massimiliano, Incerti, Matteo, Rivara, Silvia, Mor, Marco, Lodola, Alessio
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: MDPI 2015
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC6331951/
https://ncbi.nlm.nih.gov/pubmed/26393553
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules200917132
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