A second generation of carbamate-based fatty acid amide hydrolase inhibitors with improved activity in vivo

The fatty acid ethanolamides are a class of signaling lipids that include agonists at cannabinoid and type-α peroxisome proliferator-activated receptors. In the brain, these compounds are primarily hydrolyzed by the intracellular serine enzyme fatty acid amide hydrolase (FAAH). O-aryl carbamate FAAH...

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Detalhes bibliográficos
Main Authors: Clapper, Jason R., Vacondio, Federica, King, Alvin R., Duranti, Andrea, Tontini, Andrea, Silva, Claudia, Sanchini, Silvano, Tarzia, Giorgio, Mor, Marco, Piomelli, Daniele
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3016090/
https://ncbi.nlm.nih.gov/pubmed/19637155
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cmdc.200900210
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