Synthesis and QSAR of Fatty Acid Amide Hydrolase Inhibitors: Modulation at the N-Portion of Biphenyl-3-yl Alkylcarbamates

Alkylcarbamic acid biphenyl-3-yl esters are a class of fatty acid amide hydrolase (FAAH) inhibitors that comprises cyclohexylcarbamic acid 3′-carbamoylbiphenyl-3-yl ester (URB597), a compound with analgesic, anxiolytic-like and antidepressant-like properties in rat and mouse models. Here, we extende...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Mor, Marco, Lodola, Alessio, Rivara, Silvia, Vacondio, Federica, Duranti, Andrea, Tontini, Andrea, Sanchini, Silvano, Piersanti, Giovanni, Clapper, Jason R., King, Alvin R., Tarzia, Giorgio, Piomelli, Daniele
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3744893/
https://ncbi.nlm.nih.gov/pubmed/18507372
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jm701631z
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados