Fasudil, a clinically-safe ROCK Inhibitor, Decreases Disease Burden in a Cbl/Cbl-b Deficiency-Driven Murine Model of Myeloproliferative Disorders

Por William, Basem M., An, Wei, Feng, Dan, Nadeau, Scott, Mohapatra, Bhopal C, Storck, Matthew A., Band, Vimla, Band, Hamid
Publicado no Hematology (2015)

A novel CBL-B(flox/flox) mouse model allows tissue-selective fully conditional CBL/CBL-B double-knockout: CD4-Cre mediated CBL/CBL-B deletion occurs in both T-cells and hematopoiet...

Por Goetz, Benjamin, An, Wei, Mohapatra, Bhopal, Zutshi, Neha, Iseka, Fany, Storck, Matthew D., Meza, Jane, Sheinin, Yuri, Band, Vimla, Band, Hamid
Publicado no Oncotarget (2016)

Mutant Cbl proteins as oncogenic drivers in myeloproliferative disorders

Por Naramura, Mayumi, Nadeau, Scott, Mohapatra, Bhopal, Ahmad, Gulzar, Mukhopadhyay, Chandrani, Sattler, Martin, Raja, Srikumar M, Natarajan, Amarnath, Band, Vimla, Band, Hamid
Publicado em 2011

The Endocytic Recycling Regulatory Protein EHD1 Is Required for Ocular Lens Development

Por Arya, Priyanka, Rainey, Mark A., Bhattacharyya, Sohinee, Mohapatra, Bhopal, George, Manju, Kuracha, Murali R, Storck, Matthew D., Band, Vimla, Govindarajan, Venkatesh, Band, Hamid
Publicado no Dev Biol (2015)

VAV1-Cre mediated hematopoietic deletion of CBL and CBL-B leads to JMML-like aggressive early-neonatal myeloproliferative disease

Por An, Wei, Mohapatra, Bhopal C., Zutshi, Neha, Bielecki, Timothy A., Goez, Benjamin T., Luan, Haitao, Iseka, Fany, Mushtaq, Insha, Storck, Matthew D., Band, Vimla, Band, Hamid
Publicado no Oncotarget (2016)

An essential role of CBL and CBL-B ubiquitin ligases in mammary stem cell maintenance

Por Mohapatra, Bhopal, Zutshi, Neha, An, Wei, Goetz, Benjamin, Arya, Priyanka, Bielecki, Timothy A., Mustaq, Insha, Storck, Matthew D., Meza, Jane L., Band, Vimla, Band, Hamid
Publicado no Development (2017)

Loss of Cbl and Cbl-b ubiquitin ligases abrogates hematopoietic stem cell quiescence and sensitizes leukemic disease to chemotherapy

Por An, Wei, Nadeau, Scott A., Mohapatra, Bhopal C., Feng, Dan, Zutshi, Neha, Storck, Matthew D., Arya, Priyanka, Talmadge, James E., Meza, Jane L., Band, Vimla, Band, Hamid
Publicado no Oncotarget (2015)

ESCRT proteins: Double-edged regulators of cellular signaling

Por Tu, Chun, Ahmad, Gulzar, Mohapatra, Bhopal, Bhattacharyya, Sohinee, Ortega-Cava, Cesar F, Chung, Byung Min, Wagner, Kay-Uwe, Raja, Srikumar M, Naramura, Mayumi, Band, Vimla, Band, Hamid
Publicado em 2011

A Kinase Inhibitor Screen Reveals Protein Kinase C-dependent Endocytic Recycling of ErbB2 in Breast Cancer Cells

Por Bailey, Tameka A., Luan, Haitao, Tom, Eric, Bielecki, Timothy Alan, Mohapatra, Bhopal, Ahmad, Gulzar, George, Manju, Kelly, David L., Natarajan, Amarnath, Raja, Srikumar M., Band, Vimla, Band, Hamid
Publicado em 2014

c-Cbl Inhibition Improves Cardiac function and Survival in Response to Myocardial Ischemia

Por Rafiq, Khadija, Kolpakov, Mikhail A, Seqqat, Rachid, Guo, Jianfen, Guo, Xinji, Qi, Zhao, Yu, Daohai, Mohapatra, Bhopal, Zutshi, Neha, An, Wei, Band, Hamid, Sanjay, Archana, Houser, Steven R, Sabri, Abdelkarim
Publicado em 2014

Structural Determinants of the Gain-of-Function Phenotype of Human Leukemia-associated Mutant CBL Oncogene

Por Nadeau, Scott A., An, Wei, Mohapatra, Bhopal C., Mushtaq, Insha, Bielecki, Timothy A., Luan, Haitao, Zutshi, Neha, Ahmad, Gulzar, Storck, Matthew D., Sanada, Masashi, Ogawa, Seishi, Band, Vimla, Band, Hamid
Publicado no J Biol Chem (2017)

Cbl-family ubiquitin ligases and their recruitment of CIN85 are largely dispensable for epidermal growth factor receptor endocytosis

Por Ahmad, Gulzar, Mohapatra, Bhopal, Schulte, Nancy A., Nadeau, Scott, Luan, Haitao, Zutshi, Neha, Tom, Eric, Ortega-Cava, Cesar, Tu, Chun, Sanada, Masashi, Ogawa, Seishi, Toews, Myron L., Band, Vimla, Band, Hamid
Publicado no Int J Biochem Cell Biol (2014)

Marked enhancement of lysosomal targeting and efficacy of ErbB2-targeted drug delivery by HSP90 inhibition

Por Raja, Srikumar M., Desale, Swapnil S., Mohapatra, Bhopal, Luan, Haitao, Soni, Kruti, Zhang, Jinjin, Storck, Matthew A., Feng, Dan, Bielecki, Timothy A., Band, Vimla, Cohen, Samuel M., Bronich, Tatiana K., Band, Hamid
Publicado no Oncotarget (2016)

Continuous requirement of ErbB2 kinase activity for loss of cell polarity and lumen formation in a novel ErbB2/Neu-driven murine cell line model of metastatic breast cancer

Por Ortega-Cava, Cesar F., Raja, Srikumar M., Laiq, Zenab, Bailey, Tameka A., Luan, Haitao, Mohapatra, Bhopal, Williams, Stetson H., Ericsson, Aaron C., Goswami, Rasna, Dimri, Manjari, Duan, Lei, Band, Vimla, Naramura, Mayumi, Band, Hamid
Publicado em 2011

Polypeptide-based nanogels co-encapsulating a synergistic combination of Doxorubicin with 17-AAG show potent anti-tumor activity in ErbB2-driven breast cancer models

Por Desale, Swapnil S., Raja, Srikumar M., Kim, Jong Oh, Mohapatra, Bhopal, Soni, Kruti S., Luan, Haitao, Williams, Stetson H., Bielecki, Tim A, Feng, Dan, Storck, Matthew, Band, Vimla, Cohen, Samuel M., Band, Hamid, Bronich, Tatiana K.
Publicado no J Control Release (2015)

Protein tyrosine kinase regulation by ubiquitination: Critical roles of Cbl-family ubiquitin ligases

Por Mohapatra, Bhopal, Ahmad, Gulzar, Nadeau, Scott, Zutshi, Neha, An, Wei, Scheffe, Sarah, Dong, Lin, Feng, Dan, Goetz, Benjamin, Arya, Priyanka, Bailey, Tameka A., Palermo, Nicholas, Borgstahl, Gloria E.O., Natarajan, Amarnath, Raja, Srikumar M., Naramura, Mayumi, Band, Vimla, Band, Hamid
Publicado em 2012

Corrigendum: Endocytic recycling protein EHD1 regulates primary cilia morphogenesis and SHH signaling during neural tube development

Por Bhattacharyya, Sohinee, Rainey, Mark A., Arya, Priyanka, Mohapatra, Bhopal C., Mushtaq, Insha, Dutta, Samikshan, George, Manju, Storck, Matthew D., McComb, Rodney D., Muirhead, David, Todd, Gordon L., Gould, Karen, Datta, Kaustubh, Waes, Janee Gelineau-van, Band, Vimla, Band, Hamid
Publicado no Sci Rep (2017)

CBL family E3 ubiquitin ligases control JAK2 ubiquitination and stability in hematopoietic stem cells and myeloid malignancies

Por Lv, Kaosheng, Jiang, Jing, Donaghy, Ryan, Riling, Christopher R., Cheng, Ying, Chandra, Vemika, Rozenova, Krasimira, An, Wei, Mohapatra, Bhopal C., Goetz, Benjamin T., Pillai, Vinodh, Han, Xu, Todd, Emily A., Jeschke, Grace R., Langdon, Wallace Y., Kumar, Suresh, Hexner, Elizabeth O., Band, Hamid, Tong, Wei
Publicado no Genes Dev (2017)