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Marked enhancement of lysosomal targeting and efficacy of ErbB2-targeted drug delivery by HSP90 inhibition

Targeted delivery of anticancer drugs to tumor cells using monoclonal antibodies against oncogenic cell surface receptors is an emerging therapeutic strategy. These strategies include drugs directly conjugated to monoclonal antibodies through chemical linkers (Antibody-Drug Conjugates, ADCs) or thos...

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Dades bibliogràfiques
Publicat a:Oncotarget
Autors principals: Raja, Srikumar M., Desale, Swapnil S., Mohapatra, Bhopal, Luan, Haitao, Soni, Kruti, Zhang, Jinjin, Storck, Matthew A., Feng, Dan, Bielecki, Timothy A., Band, Vimla, Cohen, Samuel M., Bronich, Tatiana K., Band, Hamid
Format: Artigo
Idioma:Inglês
Publicat: Impact Journals LLC 2016
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4891137/
https://ncbi.nlm.nih.gov/pubmed/26859680
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.7231
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