Marked enhancement of lysosomal targeting and efficacy of ErbB2-targeted drug delivery by HSP90 inhibition

Targeted delivery of anticancer drugs to tumor cells using monoclonal antibodies against oncogenic cell surface receptors is an emerging therapeutic strategy. These strategies include drugs directly conjugated to monoclonal antibodies through chemical linkers (Antibody-Drug Conjugates, ADCs) or thos...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Raja, Srikumar M., Desale, Swapnil S., Mohapatra, Bhopal, Luan, Haitao, Soni, Kruti, Zhang, Jinjin, Storck, Matthew A., Feng, Dan, Bielecki, Timothy A., Band, Vimla, Cohen, Samuel M., Bronich, Tatiana K., Band, Hamid
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2016
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4891137/
https://ncbi.nlm.nih.gov/pubmed/26859680
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.7231
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