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An essential role of CBL and CBL-B ubiquitin ligases in mammary stem cell maintenance
The ubiquitin ligases CBL and CBL-B are negative regulators of tyrosine kinase signaling with established roles in the immune system. However, their physiological roles in epithelial tissues are unknown. Here, we used MMTV-Cre-mediated Cbl gene deletion on a Cbl-b null background, as well as a tamox...
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| Yayımlandı: | Development |
|---|---|
| Asıl Yazarlar: | , , , , , , , , , , |
| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
The Company of Biologists Ltd
2017
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| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5358102/ https://ncbi.nlm.nih.gov/pubmed/28100467 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.138164 |
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