c-Cbl Inhibition Improves Cardiac function and Survival in Response to Myocardial Ischemia

BACKGROUND: The proto-oncogene Casitas b-lineage lymphoma (c-Cbl) is an adaptor protein with an intrinsic E3 ubiquitin ligase activity that targets receptor and non-receptor tyrosine kinases, resulting in their ubiquitination and down-regulation. However, the function of c-Cbl in the control of card...

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Detalhes bibliográficos
Main Authors: Rafiq, Khadija, Kolpakov, Mikhail A, Seqqat, Rachid, Guo, Jianfen, Guo, Xinji, Qi, Zhao, Yu, Daohai, Mohapatra, Bhopal, Zutshi, Neha, An, Wei, Band, Hamid, Sanjay, Archana, Houser, Steven R, Sabri, Abdelkarim
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4045410/
https://ncbi.nlm.nih.gov/pubmed/24583314
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCULATIONAHA.113.007004
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