TGFβ-induced Lung Cancer Cell Migration is NR4A1-dependent

por Hedrick, Erik, Mohankumar, Kumaravel, Safe, Stephen
Publicado no Mol Cancer Res (2018)

Bis-indole derived nuclear receptor 4A1 (NR4A1) antagonists inhibit TGFβ-induced invasion of embryonal rhabdomyosarcoma cells

por Shrestha, Rupesh, Mohankumar, Kumaravel, Safe, Stephen
Publicado no Am J Cancer Res (2020)

INHIBITION OF NR4A1 PROMOTES ROS ACCUMULATION AND IL-24 – DEPENDENT GROWTH ARREST IN RHABDOMYOSARCOMA

por Hedrick, Erik, Mohankumar, Kumaravel, Lacey, Alexandra, Safe, Stephen
Publicado no Mol Cancer Res (2019)

Antiproliferative and Apoptotic Effects of Sesbania grandiflora Leaves in Human Cancer Cells

por Pajaniradje, Sankar, Mohankumar, Kumaravel, Pamidimukkala, Ramya, Subramanian, Srividya, Rajagopalan, Rukkumani
Publicado em 2014

Nuclear Receptor 4A1 (NR4A1) Antagonists Induce ROS-dependent Inhibition of mTOR Signaling in Endometrial Cancer

por Mohankumar, Kumaravel, Li, Xi, Sridharan, Subhashree, Karki, Keshav, Safe, Stephen
Publicado no Gynecol Oncol (2019)

Aryl Hydrocarbon Receptor (AhR) Ligands as Selective AhR Modulators: Genomic Studies

por Safe, Stephen, Han, Huajun, Goldsby, Jennifer, Mohankumar, Kumaravel, Chapkin, Robert S.
Publicado no Curr Opin Toxicol (2018)

Bis-Indole–Derived NR4A1 Ligands and Metformin Exhibit NR4A1-Dependent Glucose Metabolism and Uptake in C2C12 Cells

por Mohankumar, Kumaravel, Lee, Jehoon, Wu, Chia Shan, Sun, Yuxiang, Safe, Stephen
Publicado no Endocrinology (2018)

INTERLEUKIN-24 (IL-24) IS SUPPRESSED BY PAX3-FOXO1 AND IS A NOVEL THERAPY FOR RHABDOMYOSARCOMA

por Lacey, Alexandra, Hedrick, Erik, Cheng, Yating, Mohankumar, Kumaravel, Warren, Melanie, Safe, Stephen
Publicado no Mol Cancer Ther (2018)

Reactive Oxygen Species (ROS)-Inducing Triterpenoid Inhibits Rhabdomyosarcoma Cell and Tumor Growth Through Targeting Sp Transcription Factors

por Kasiappan, Ravi, Jutooru, Indira, Mohankumar, Kumaravel, Karki, Keshav, Lacey, Alexandra, Safe, Stephen
Publicado no Mol Cancer Res (2019)

THE HISTONE METHYLTRANSFERASE GENE G9A IS REGULATED BY NUCLEAR RECEPTOR 4A1 (NR4A1) IN ALVEOLAR RHABDOMYOSARCOMA CELLS

por Shrestha, Rupesh, Mohankumar, Kumaravel, Jin, Un-ho, Martin, Gregory G., Safe, Stephen
Publicado no Mol Cancer Ther (2020)

Flavonoids: structure–function and mechanisms of action and opportunities for drug development

por Safe, Stephen, Jayaraman, Arul, Chapkin, Robert S., Howard, Marcell, Mohankumar, Kumaravel, Shrestha, Rupesh
Publicado no Toxicol Res (2021)

NR4A1 Ligands as Potent Inhibitors of Breast Cancer Cell and Tumor Growth

por Karki, Keshav, Mohankumar, Kumaravel, Schoeller, Abigail, Martin, Gregory, Shrestha, Rupesh, Safe, Stephen
Publicado no Cancers (Basel) (2021)

Potent Inhibition of Breast Cancer by Bis-Indole-Derived Nuclear Receptor 4A1 (NR4A1) Antagonists

por Hedrick, Erik, Li, Xi, Cheng, Yating, Lacey, Alexandra, Mohankumar, Kumaravel, Zarei, Mahsa, Safe, Stephen
Publicado no Breast Cancer Res Treat (2019)

Bis-Indole–Derived Nuclear Receptor 4A1 (NR4A1, Nur77) Ligands as Inhibitors of Endometriosis

por Mohankumar, Kumaravel, Li, Xi, Sung, Nuri, Cho, Yeon Jean, Han, Sang Jun, Safe, Stephen
Publicado no Endocrinology (2020)

A Bis-Indole-Derived NR4A1 Antagonist Induces PD-L1 Degradation and Enhances Anti-Tumor Immunity

por Karki, Keshav, Wright, Gus A., Mohankumar, Kumaravel, Jin, Un-Ho, Zhang, Xing-Han, Safe, Stephen
Publicado no Cancer Res (2020)

Nuclear Receptor 4A2 (NR4A2) Is a Druggable Target for Glioblastomas

por Karki, Keshav, Li, Xi, Jin, Un-Ho, Mohankumar, Kumaravel, Zarei, Mahsa, Michelhaugh, Sharon K., Mittal, Sandeep, Tjalkens, Ronald, Safe, Stephen
Publicado no J Neurooncol (2019)

Genetic and functional characterization of HIV-1 Vif on APOBEC3G degradation: First report of emergence of B/C recombinants from North India

por Ronsard, Larance, Raja, Rameez, Panwar, Vaishali, Saini, Sanjesh, Mohankumar, Kumaravel, Sridharan, Subhashree, Padmapriya, Ramamoorthy, Chaudhuri, Suhnrita, Ramachandran, Vishnampettai G, Banerjea, Akhil C
Publicado no Sci Rep (2015)

Genetic Polymorphisms in the Open Reading Frame of the CCR5 gene From HIV-1 Seronegative and Seropositive Individuals From National Capital Regions of India

por Ronsard, Larance, Sood, Vikas, Yousif, Ashraf S., Ramesh, Janani, Shankar, Vijay, Das, Jishnu, Sumi, N., Rai, Tripti, Mohankumar, Kumaravel, Sridharan, Subhashree, Dorschel, Arianna, Ramachandran, Vishnampettai G., Banerjea, Akhil C.
Publicado no Sci Rep (2019)

Impact of Genetic Variations in HIV-1 Tat on LTR-Mediated Transcription via TAR RNA Interaction

por Ronsard, Larance, Ganguli, Nilanjana, Singh, Vivek K., Mohankumar, Kumaravel, Rai, Tripti, Sridharan, Subhashree, Pajaniradje, Sankar, Kumar, Binod, Rai, Devesh, Chaudhuri, Suhnrita, Coumar, Mohane S., Ramachandran, Vishnampettai G., Banerjea, Akhil C.
Publicado no Front Microbiol (2017)