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INTERLEUKIN-24 (IL-24) IS SUPPRESSED BY PAX3-FOXO1 AND IS A NOVEL THERAPY FOR RHABDOMYOSARCOMA
Alveolar Rhabdomyosarcoma (ARMS) patients have a poor prognosis and this is primarily due to overexpression of the oncogenic fusion protein PAX3-FOXO1. Results of RNASeq studies show that PAX3-FOXO1 represses expression of interleukin-24 (IL-24) and these two genes are inversely expressed in patient...
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| 出版年: | Mol Cancer Ther |
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| 主要な著者: | , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2018
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6279487/ https://ncbi.nlm.nih.gov/pubmed/30190424 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1535-7163.MCT-18-0118 |
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