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TGFβ-induced Lung Cancer Cell Migration is NR4A1-dependent

Transforming growth factor β (TGFβ) induces migration of lung cancer cells (A549, H460 and H1299), dependent on activation of c-Jun N-terminal kinase (JNK1), and is inhibited by the JNK1 inhibitor SP600125. Moreover, TGFβ-induced migration of the cells is also blocked by the nuclear export inhibitor...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Mol Cancer Res
Hauptverfasser: Hedrick, Erik, Mohankumar, Kumaravel, Safe, Stephen
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2018
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6343492/
https://ncbi.nlm.nih.gov/pubmed/30072581
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1541-7786.MCR-18-0366
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