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Transforming Growth Factor β/NR4A1-Inducible Breast Cancer Cell Migration and Epithelial-to-Mesenchymal Transition Is p38α (Mitogen-Activated Protein Kinase 14) Dependent

Transforming growth factor β (TGF-β)-induced migration of triple-negative breast cancer (TNBC) cells is dependent on nuclear export of the orphan receptor NR4A1, which plays a role in proteasome-dependent degradation of SMAD7. In this study, we show that TGF-β induces p38α (mitogen-activated protein...

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Detalhes bibliográficos
Publicado no:Mol Cell Biol
Main Authors: Hedrick, Erik, Safe, Stephen
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5574050/
https://ncbi.nlm.nih.gov/pubmed/28674186
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00306-17
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