Impact of Genetic Variations in HIV-1 Tat on LTR-Mediated Transcription via TAR RNA Interaction

HIV-1 evades host defense through mutations and recombination events, generating numerous variants in an infected patient. These variants with an undiminished virulence can multiply rapidly in order to progress to AIDS. One of the targets to intervene in HIV-1 replication is the trans-activator of t...

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Vydáno v:Front Microbiol
Hlavní autoři: Ronsard, Larance, Ganguli, Nilanjana, Singh, Vivek K., Mohankumar, Kumaravel, Rai, Tripti, Sridharan, Subhashree, Pajaniradje, Sankar, Kumar, Binod, Rai, Devesh, Chaudhuri, Suhnrita, Coumar, Mohane S., Ramachandran, Vishnampettai G., Banerjea, Akhil C.
Médium: Artigo
Jazyk:Inglês
Vydáno: Frontiers Media S.A. 2017
Témata:
Microbiology
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5399533/
https://ncbi.nlm.nih.gov/pubmed/28484443
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fmicb.2017.00706
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