TGFβ-induced Lung Cancer Cell Migration is NR4A1-dependent

par Hedrick, Erik, Mohankumar, Kumaravel, Safe, Stephen
Publié dans Mol Cancer Res (2018)

Bis-indole derived nuclear receptor 4A1 (NR4A1) antagonists inhibit TGFβ-induced invasion of embryonal rhabdomyosarcoma cells

par Shrestha, Rupesh, Mohankumar, Kumaravel, Safe, Stephen
Publié dans Am J Cancer Res (2020)

INHIBITION OF NR4A1 PROMOTES ROS ACCUMULATION AND IL-24 – DEPENDENT GROWTH ARREST IN RHABDOMYOSARCOMA

par Hedrick, Erik, Mohankumar, Kumaravel, Lacey, Alexandra, Safe, Stephen
Publié dans Mol Cancer Res (2019)

Antiproliferative and Apoptotic Effects of Sesbania grandiflora Leaves in Human Cancer Cells

par Pajaniradje, Sankar, Mohankumar, Kumaravel, Pamidimukkala, Ramya, Subramanian, Srividya, Rajagopalan, Rukkumani
Publié 2014

Nuclear Receptor 4A1 (NR4A1) Antagonists Induce ROS-dependent Inhibition of mTOR Signaling in Endometrial Cancer

par Mohankumar, Kumaravel, Li, Xi, Sridharan, Subhashree, Karki, Keshav, Safe, Stephen
Publié dans Gynecol Oncol (2019)

Aryl Hydrocarbon Receptor (AhR) Ligands as Selective AhR Modulators: Genomic Studies

par Safe, Stephen, Han, Huajun, Goldsby, Jennifer, Mohankumar, Kumaravel, Chapkin, Robert S.
Publié dans Curr Opin Toxicol (2018)

Bis-Indole–Derived NR4A1 Ligands and Metformin Exhibit NR4A1-Dependent Glucose Metabolism and Uptake in C2C12 Cells

par Mohankumar, Kumaravel, Lee, Jehoon, Wu, Chia Shan, Sun, Yuxiang, Safe, Stephen
Publié dans Endocrinology (2018)

INTERLEUKIN-24 (IL-24) IS SUPPRESSED BY PAX3-FOXO1 AND IS A NOVEL THERAPY FOR RHABDOMYOSARCOMA

par Lacey, Alexandra, Hedrick, Erik, Cheng, Yating, Mohankumar, Kumaravel, Warren, Melanie, Safe, Stephen
Publié dans Mol Cancer Ther (2018)

Reactive Oxygen Species (ROS)-Inducing Triterpenoid Inhibits Rhabdomyosarcoma Cell and Tumor Growth Through Targeting Sp Transcription Factors

par Kasiappan, Ravi, Jutooru, Indira, Mohankumar, Kumaravel, Karki, Keshav, Lacey, Alexandra, Safe, Stephen
Publié dans Mol Cancer Res (2019)

THE HISTONE METHYLTRANSFERASE GENE G9A IS REGULATED BY NUCLEAR RECEPTOR 4A1 (NR4A1) IN ALVEOLAR RHABDOMYOSARCOMA CELLS

par Shrestha, Rupesh, Mohankumar, Kumaravel, Jin, Un-ho, Martin, Gregory G., Safe, Stephen
Publié dans Mol Cancer Ther (2020)

Flavonoids: structure–function and mechanisms of action and opportunities for drug development

par Safe, Stephen, Jayaraman, Arul, Chapkin, Robert S., Howard, Marcell, Mohankumar, Kumaravel, Shrestha, Rupesh
Publié dans Toxicol Res (2021)

NR4A1 Ligands as Potent Inhibitors of Breast Cancer Cell and Tumor Growth

par Karki, Keshav, Mohankumar, Kumaravel, Schoeller, Abigail, Martin, Gregory, Shrestha, Rupesh, Safe, Stephen
Publié dans Cancers (Basel) (2021)

Potent Inhibition of Breast Cancer by Bis-Indole-Derived Nuclear Receptor 4A1 (NR4A1) Antagonists

par Hedrick, Erik, Li, Xi, Cheng, Yating, Lacey, Alexandra, Mohankumar, Kumaravel, Zarei, Mahsa, Safe, Stephen
Publié dans Breast Cancer Res Treat (2019)

Bis-Indole–Derived Nuclear Receptor 4A1 (NR4A1, Nur77) Ligands as Inhibitors of Endometriosis

par Mohankumar, Kumaravel, Li, Xi, Sung, Nuri, Cho, Yeon Jean, Han, Sang Jun, Safe, Stephen
Publié dans Endocrinology (2020)

A Bis-Indole-Derived NR4A1 Antagonist Induces PD-L1 Degradation and Enhances Anti-Tumor Immunity

par Karki, Keshav, Wright, Gus A., Mohankumar, Kumaravel, Jin, Un-Ho, Zhang, Xing-Han, Safe, Stephen
Publié dans Cancer Res (2020)

Nuclear Receptor 4A2 (NR4A2) Is a Druggable Target for Glioblastomas

par Karki, Keshav, Li, Xi, Jin, Un-Ho, Mohankumar, Kumaravel, Zarei, Mahsa, Michelhaugh, Sharon K., Mittal, Sandeep, Tjalkens, Ronald, Safe, Stephen
Publié dans J Neurooncol (2019)

Genetic and functional characterization of HIV-1 Vif on APOBEC3G degradation: First report of emergence of B/C recombinants from North India

par Ronsard, Larance, Raja, Rameez, Panwar, Vaishali, Saini, Sanjesh, Mohankumar, Kumaravel, Sridharan, Subhashree, Padmapriya, Ramamoorthy, Chaudhuri, Suhnrita, Ramachandran, Vishnampettai G, Banerjea, Akhil C
Publié dans Sci Rep (2015)

Genetic Polymorphisms in the Open Reading Frame of the CCR5 gene From HIV-1 Seronegative and Seropositive Individuals From National Capital Regions of India

par Ronsard, Larance, Sood, Vikas, Yousif, Ashraf S., Ramesh, Janani, Shankar, Vijay, Das, Jishnu, Sumi, N., Rai, Tripti, Mohankumar, Kumaravel, Sridharan, Subhashree, Dorschel, Arianna, Ramachandran, Vishnampettai G., Banerjea, Akhil C.
Publié dans Sci Rep (2019)

Impact of Genetic Variations in HIV-1 Tat on LTR-Mediated Transcription via TAR RNA Interaction

par Ronsard, Larance, Ganguli, Nilanjana, Singh, Vivek K., Mohankumar, Kumaravel, Rai, Tripti, Sridharan, Subhashree, Pajaniradje, Sankar, Kumar, Binod, Rai, Devesh, Chaudhuri, Suhnrita, Coumar, Mohane S., Ramachandran, Vishnampettai G., Banerjea, Akhil C.
Publié dans Front Microbiol (2017)