TGFβ-induced Lung Cancer Cell Migration is NR4A1-dependent

by Hedrick, Erik, Mohankumar, Kumaravel, Safe, Stephen
Published in Mol Cancer Res (2018)

Bis-indole derived nuclear receptor 4A1 (NR4A1) antagonists inhibit TGFβ-induced invasion of embryonal rhabdomyosarcoma cells

by Shrestha, Rupesh, Mohankumar, Kumaravel, Safe, Stephen
Published in Am J Cancer Res (2020)

INHIBITION OF NR4A1 PROMOTES ROS ACCUMULATION AND IL-24 – DEPENDENT GROWTH ARREST IN RHABDOMYOSARCOMA

by Hedrick, Erik, Mohankumar, Kumaravel, Lacey, Alexandra, Safe, Stephen
Published in Mol Cancer Res (2019)

Antiproliferative and Apoptotic Effects of Sesbania grandiflora Leaves in Human Cancer Cells

by Pajaniradje, Sankar, Mohankumar, Kumaravel, Pamidimukkala, Ramya, Subramanian, Srividya, Rajagopalan, Rukkumani
Published 2014

Nuclear Receptor 4A1 (NR4A1) Antagonists Induce ROS-dependent Inhibition of mTOR Signaling in Endometrial Cancer

by Mohankumar, Kumaravel, Li, Xi, Sridharan, Subhashree, Karki, Keshav, Safe, Stephen
Published in Gynecol Oncol (2019)

Aryl Hydrocarbon Receptor (AhR) Ligands as Selective AhR Modulators: Genomic Studies

by Safe, Stephen, Han, Huajun, Goldsby, Jennifer, Mohankumar, Kumaravel, Chapkin, Robert S.
Published in Curr Opin Toxicol (2018)

Bis-Indole–Derived NR4A1 Ligands and Metformin Exhibit NR4A1-Dependent Glucose Metabolism and Uptake in C2C12 Cells

by Mohankumar, Kumaravel, Lee, Jehoon, Wu, Chia Shan, Sun, Yuxiang, Safe, Stephen
Published in Endocrinology (2018)

INTERLEUKIN-24 (IL-24) IS SUPPRESSED BY PAX3-FOXO1 AND IS A NOVEL THERAPY FOR RHABDOMYOSARCOMA

by Lacey, Alexandra, Hedrick, Erik, Cheng, Yating, Mohankumar, Kumaravel, Warren, Melanie, Safe, Stephen
Published in Mol Cancer Ther (2018)

Reactive Oxygen Species (ROS)-Inducing Triterpenoid Inhibits Rhabdomyosarcoma Cell and Tumor Growth Through Targeting Sp Transcription Factors

by Kasiappan, Ravi, Jutooru, Indira, Mohankumar, Kumaravel, Karki, Keshav, Lacey, Alexandra, Safe, Stephen
Published in Mol Cancer Res (2019)

THE HISTONE METHYLTRANSFERASE GENE G9A IS REGULATED BY NUCLEAR RECEPTOR 4A1 (NR4A1) IN ALVEOLAR RHABDOMYOSARCOMA CELLS

by Shrestha, Rupesh, Mohankumar, Kumaravel, Jin, Un-ho, Martin, Gregory G., Safe, Stephen
Published in Mol Cancer Ther (2020)

Flavonoids: structure–function and mechanisms of action and opportunities for drug development

by Safe, Stephen, Jayaraman, Arul, Chapkin, Robert S., Howard, Marcell, Mohankumar, Kumaravel, Shrestha, Rupesh
Published in Toxicol Res (2021)

NR4A1 Ligands as Potent Inhibitors of Breast Cancer Cell and Tumor Growth

by Karki, Keshav, Mohankumar, Kumaravel, Schoeller, Abigail, Martin, Gregory, Shrestha, Rupesh, Safe, Stephen
Published in Cancers (Basel) (2021)

Potent Inhibition of Breast Cancer by Bis-Indole-Derived Nuclear Receptor 4A1 (NR4A1) Antagonists

by Hedrick, Erik, Li, Xi, Cheng, Yating, Lacey, Alexandra, Mohankumar, Kumaravel, Zarei, Mahsa, Safe, Stephen
Published in Breast Cancer Res Treat (2019)

Bis-Indole–Derived Nuclear Receptor 4A1 (NR4A1, Nur77) Ligands as Inhibitors of Endometriosis

by Mohankumar, Kumaravel, Li, Xi, Sung, Nuri, Cho, Yeon Jean, Han, Sang Jun, Safe, Stephen
Published in Endocrinology (2020)

A Bis-Indole-Derived NR4A1 Antagonist Induces PD-L1 Degradation and Enhances Anti-Tumor Immunity

by Karki, Keshav, Wright, Gus A., Mohankumar, Kumaravel, Jin, Un-Ho, Zhang, Xing-Han, Safe, Stephen
Published in Cancer Res (2020)

Nuclear Receptor 4A2 (NR4A2) Is a Druggable Target for Glioblastomas

by Karki, Keshav, Li, Xi, Jin, Un-Ho, Mohankumar, Kumaravel, Zarei, Mahsa, Michelhaugh, Sharon K., Mittal, Sandeep, Tjalkens, Ronald, Safe, Stephen
Published in J Neurooncol (2019)

Genetic and functional characterization of HIV-1 Vif on APOBEC3G degradation: First report of emergence of B/C recombinants from North India

by Ronsard, Larance, Raja, Rameez, Panwar, Vaishali, Saini, Sanjesh, Mohankumar, Kumaravel, Sridharan, Subhashree, Padmapriya, Ramamoorthy, Chaudhuri, Suhnrita, Ramachandran, Vishnampettai G, Banerjea, Akhil C
Published in Sci Rep (2015)

Genetic Polymorphisms in the Open Reading Frame of the CCR5 gene From HIV-1 Seronegative and Seropositive Individuals From National Capital Regions of India

by Ronsard, Larance, Sood, Vikas, Yousif, Ashraf S., Ramesh, Janani, Shankar, Vijay, Das, Jishnu, Sumi, N., Rai, Tripti, Mohankumar, Kumaravel, Sridharan, Subhashree, Dorschel, Arianna, Ramachandran, Vishnampettai G., Banerjea, Akhil C.
Published in Sci Rep (2019)

Impact of Genetic Variations in HIV-1 Tat on LTR-Mediated Transcription via TAR RNA Interaction

by Ronsard, Larance, Ganguli, Nilanjana, Singh, Vivek K., Mohankumar, Kumaravel, Rai, Tripti, Sridharan, Subhashree, Pajaniradje, Sankar, Kumar, Binod, Rai, Devesh, Chaudhuri, Suhnrita, Coumar, Mohane S., Ramachandran, Vishnampettai G., Banerjea, Akhil C.
Published in Front Microbiol (2017)