AKT inhibition mitigates terminal differentiation and preserves central memory phenotype of CD8 T cells

Tekijä Abu Eid, Rasha, Friedman, Kevin, Mkrtichyan, Mikayel, Khleif, Samir N
Julkaisussa J Immunother Cancer (2014)

SANTAVAC(TM): Summary of Research and Development

Tekijä Lokhov, Petr G., Mkrtichyan, Mikayel, Mamikonyan, Grigor, Balashova, Elena E.
Julkaisussa Vaccines (Basel) (2019)

Functional redundancy of PI3K isoforms in conventional T cells provides a selective Treg-targeting strategy through inhibition of PI3K-delta isoform

Tekijä Ahmad, Shamim, Mkrtichyan, Mikayel, Eid, Rasha Abu, Shrimali, Rajeev, Doroodchi, Atbin, Khleif, Samir N
Julkaisussa J Immunother Cancer (2014)

Prototype Alzheimer’s disease epitope vaccine induced strong Th2-type anti-Aβ antibody response with Alum to Quil A adjuvant switch

Tekijä Ghochikyan, Anahit, Mkrtichyan, Mikayel, Petrushina, Irina, Movsesyan, Nina, Karapetyan, Adrine, Cribbs, David H., Agadjanyan, Michael G.
Julkaistu 2005

Anti-PD-1 antibody significantly increases therapeutic efficacy of Listeria monocytogenes (Lm)-LLO immunotherapy

Tekijä Mkrtichyan, Mikayel, Chong, Namju, Abu Eid, Rasha, Wallecha, Anu, Singh, Reshma, Rothman, John, Khleif, Samir N
Julkaistu 2013

DNA epitope vaccine containing complement component C3d enhances anti-amyloid-β antibody production and polarizes the immune response towards a Th2 phenotype

Tekijä Movsesyan, Nina, Mkrtichyan, Mikayel, Petrushina, Irina, Ross, Ted M., Cribbs, David H., Agadjanyan, Michael G., Ghochikyan, Anahit
Julkaistu 2008

Akt1 and -2 inhibition diminishes terminal differentiation and enhances central memory CD8(+) T-cell proliferation and survival

Tekijä Abu Eid, Rasha, Friedman, Kevin M, Mkrtichyan, Mikayel, Walens, Andrea, King, William, Janik, John, Khleif, Samir N
Julkaisussa Oncoimmunology (2015)

B7-DC-Ig enhances vaccine effect by a novel mechanism dependent on PD-1 expression level on T cell subsets

Tekijä Mkrtichyan, Mikayel, Najjar, Yana G., Raulfs, Estella C., Liu, Linda, Langerman, Solomon, Guittard, Geoffrey, Ozbun, Laurent, Khleif, Samir N.
Julkaisussa J Immunol (2012)

Low Concentrations of Anti-Aβ Antibodies Generated in Tg2576 Mice by DNA Epitope Vaccine Fused with 3C3d Molecular Adjuvant Do Not Affect AD Pathology

Tekijä Movsesyan, Nina, Davtyan, Hayk, Mkrtichyan, Mikayel, Petrushina, Irina, Tiraturyan, Tigran, Ross, Ted, Agadjanyan, Michael G., Ghochikyan, Anahit, Cribbs, David H.
Julkaistu 2010

Anti-PD-1 synergizes with cyclophosphamide to induce potent anti-tumor vaccine effects through novel mechanisms

Tekijä Mkrtichyan, Mikayel, Najjar, Yana G, Raulfs, Estella C, Abdalla, Maher Y, Samara, Raed, Rotem-Yehudar, Rinat, Cook, Larry, Khleif, Samir N
Julkaisussa Eur J Immunol (2011)

Single variable domains from the T cell receptor β chain function as mono- and bifunctional CARs and TCRs

Tekijä Oh, Julyun, Warshaviak, Dora Toledo, Mkrtichyan, Mikayel, Munguia, Melanie Lisette, Lin, Abby, Chai, Falene, Pigott, Craig, Kang, Jaspal, Gallo, Michael, Kamb, Alexander
Julkaisussa Sci Rep (2019)

Reducing AD-Like Pathology in 3xTg-AD Mouse Model by DNA Epitope Vaccine — A Novel Immunotherapeutic Strategy

Tekijä Movsesyan, Nina, Ghochikyan, Anahit, Mkrtichyan, Mikayel, Petrushina, Irina, Davtyan, Hayk, Olkhanud, Purevdorj B., Head, Elizabeth, Biragyn, Arya, Cribbs, David H., Agadjanyan, Michael G.
Julkaistu 2008

Agonist anti-GITR antibody significantly enhances the therapeutic efficacy of Listeria monocytogenes-based immunotherapy

Tekijä Shrimali, Rajeev, Ahmad, Shamim, Berrong, Zuzana, Okoev, Grigori, Matevosyan, Adelaida, Razavi, Ghazaleh Shoja E., Petit, Robert, Gupta, Seema, Mkrtichyan, Mikayel, Khleif, Samir N.
Julkaisussa J Immunother Cancer (2017)

Mannan-Abeta₂₈conjugate prevents Abeta-plaque deposition, but increases microhemorrhages in the brains of vaccinated Tg2576 (APPsw) mice

Tekijä Karapetyan Adrine, Vasilevko Vitaly, Ajdari Rodmehr, Movsesyan Nina, Mamikonyan Grigor, Mkrtichyan Mikayel, Ghochikyan Anahit, Petrushina Irina, Lees Andrew, Agadjanyan Michael G, Cribbs David H
Julkaistu 2008-09-01

Immunostimulant Adjuvant Patch Enhances Humoral and Cellular Immune Responses to DNA Immunization

Tekijä Mkrtichyan, Mikayel, Ghochikyan, Anahit, Movsesyan, Nina, Karapetyan, Adrine, Begoyan, Gayane, Yu, Jianmei, Glenn, Gregory M., Ross, Ted M., Agadjanyan, Michael G., Cribbs, David H.
Julkaistu 2008

Mannan-Abeta(28 )conjugate prevents Abeta-plaque deposition, but increases microhemorrhages in the brains of vaccinated Tg2576 (APPsw) mice

Tekijä Petrushina, Irina, Ghochikyan, Anahit, Mkrtichyan, Mikayel, Mamikonyan, Grigor, Movsesyan, Nina, Ajdari, Rodmehr, Vasilevko, Vitaly, Karapetyan, Adrine, Lees, Andrew, Agadjanyan, Michael G, Cribbs, David H
Julkaistu 2008

Cancer-testis antigen, BORIS based vaccine delivered by dendritic cells is extremely effective against a very aggressive and highly metastatic mouse mammary carcinoma

Tekijä Mkrtichyan, Mikayel, Ghochikyan, Anahit, Davtyan, Hayk, Movsesyan, Nina, Loukinov, Dmitry, Lobanenkov, Victor, Cribbs, David H., Laust, Amanda K., Nelson, Edward L., Agadjanyan, Michael G.
Julkaistu 2011

Immune combinational therapy targeting OX40 and IDO synergistically enhances efficacy of a cancer vaccine

Tekijä Berrong, Zuzana, Ahmad, Shamim, Abu Eid, Rasha, El Andaloussi, Abdeljabar, Sen, Tanusree, Stewart, Ross, Hammond, Scott A, Shrimali, Rajeev, Mkrtichyan, Mikayel, Khleif, Samir N
Julkaisussa J Immunother Cancer (2014)

Elicitation of T Cell Responses to Histologically Unrelated Tumors by Immunization with the Novel Cancer-Testis Antigen, Brother of the Regulator of Imprinted Sites

Tekijä Ghochikyan, Anahit, Mkrtichyan, Mikayel, Loukinov, Dmitri, Mamikonyan, Gregory, Pack, Svetlana D., Movsesyan, Nina, Ichim, Thomas E., Cribbs, David H., Lobanenkov, Victor V., Agadjanyan, Michael G.
Julkaistu 2007

Anti-Aβ(1–11) Antibody Binds to Different β-Amyloid Species, Inhibits Fibril Formation, and Disaggregates Preformed Fibrils but Not the Most Toxic Oligomers

Tekijä Mamikonyan, Grigor, Necula, Mihaela, Mkrtichyan, Mikayel, Ghochikyan, Anahit, Petrushina, Irina, Movsesyan, Nina, Mina, Erene, Kiyatkin, Anatoly, Glabe, Charles G., Cribbs, David H., Agadjanyan, Michael G.
Julkaistu 2007