Rationale for Peptide and DNA Based Epitope Vaccines for Alzheimer’s Disease Immunotherapy

Por Ghochikyan, Anahit
Publicado em 2009

Anti-cancer mechanisms in two murine bone marrow derived-DC subsets activated with Toll-like receptor 4 agonists

Por Bagaev, Alexander, Pichugin, Aleksey, Nelson, Edward L., Agadjanyan, Michael G., Ghochikyan, Anahit, Ataullakhanov, Ravshan I.
Publicado no J Immunol (2018)

Prototype Alzheimer’s disease epitope vaccine induced strong Th2-type anti-Aβ antibody response with Alum to Quil A adjuvant switch

Por Ghochikyan, Anahit, Mkrtichyan, Mikayel, Petrushina, Irina, Movsesyan, Nina, Karapetyan, Adrine, Cribbs, David H., Agadjanyan, Michael G.
Publicado em 2005

MultiTEP platform-based AD epitope vaccine activates broad repertoire of T helper cells in non-human primates

Por Davtyan, Hayk, Ghochikyan, Anahit, Petrushina, Irina, Hovakimyan, Armine, Davtyan, Arpine, Cribbs, David H., Agadjanyan, Michael G.
Publicado em 2014

Immunogenicity of DNA- and recombinant protein-based Alzheimer Disease epitope vaccines

Por Davtyan, Hayk, Bacon, Andrew, Petrushina, Irina, Zagorski, Karen, Cribbs, David H, Ghochikyan, Anahit, Agadjanyan, Michael G
Publicado no Hum Vaccin Immunother (2014)

DNA epitope vaccine containing complement component C3d enhances anti-amyloid-β antibody production and polarizes the immune response towards a Th2 phenotype

Por Movsesyan, Nina, Mkrtichyan, Mikayel, Petrushina, Irina, Ross, Ted M., Cribbs, David H., Agadjanyan, Michael G., Ghochikyan, Anahit
Publicado em 2008

Aβ-Immunotherapy for Alzheimer's Disease Using Mannan–Amyloid-Beta Peptide Immunoconjugates

Por GHOCHIKYAN, ANAHIT, PETRUSHINA, IRINA, LEES, ANDREW, VASILEVKO, VITALY, MOVSESYAN, NINA, KARAPETYAN, ADRINE, AGADJANYAN, MICHAEL G., CRIBBS, DAVID H.
Publicado em 2006

Immunogenicity of epitope vaccines targeting different B cell antigenic determinants of human α-Synuclein: Feasibility study

Por Ghochikyan, Anahit, Petrushina, Irina, Davtyan, Hayk, Hovakimyan, Armine, Saing, Tommy, Davtyan, Arpine, Cribbs, David H., Agadjanyan, Michael G.
Publicado em 2013

Comparison of Efficacy of Preventive and Therapeutic Vaccines Targeting the N Terminus of β-Amyloid in an Animal Model of Alzheimer’s Disease

Por Petrushina, Irina, Davtyan, Hayk, Hovakimyan, Armine, Davtyan, Arpine, Passos, Giselle F., Cribbs, David H., Ghochikyan, Anahit, Agadjanyan, Michael G.
Publicado no Mol Ther (2017)

Low Concentrations of Anti-Aβ Antibodies Generated in Tg2576 Mice by DNA Epitope Vaccine Fused with 3C3d Molecular Adjuvant Do Not Affect AD Pathology

Por Movsesyan, Nina, Davtyan, Hayk, Mkrtichyan, Mikayel, Petrushina, Irina, Tiraturyan, Tigran, Ross, Ted, Agadjanyan, Michael G., Ghochikyan, Anahit, Cribbs, David H.
Publicado em 2010

Refinement of a DNA based Alzheimer disease epitope vaccine in rabbits

Por Ghochikyan, Anahit, Davtyan, Hayk, Petrushina, Irina, Hovakimyan, Armine, Movsesyan, Nina, Davtyan, Arpine, Kiyatkin, Anatoly, Cribbs, David H., Agadjanyan, Michael G.
Publicado em 2013

Delivery of a DNA Vaccine for Alzheimer's Disease by Electroporation versus Gene Gun Generates Potent and Similar Immune Responses

Por Davtyan, Hayk, Ghochikyan, Anahit, Movsesyan, Nina, Ellefsen, Barry, Petrushina, Irina, Cribbs, David H., Hannaman, Drew, Evans, Claire F., Agadjanyan, Michael G.
Publicado em 2012

Epitope-based DNA vaccine for Alzheimer’s disease: translational study in macaques

Por Evans, Claire F., Davtyan, Hayk, Petrushina, Irina, Hovakimyan, Armine, Davtyan, Arpine, Hannaman, Drew, Cribbs, David H., Agadjanyan, Michael G., Ghochikyan, Anahit
Publicado em 2013

Primary 4T1 tumor resection provides critical “window of opportunity” for immunotherapy

Por Ghochikyan, Anahit, Davtyan, Arpine, Hovakimyan, Armine, Davtyan, Hayk, Poghosyan, Anna, Bagaev, Alexander, Ataullakhanov, Ravshan I, Nelson, Edward L., Agadjanyan, Michael G.
Publicado em 2013

Arginine Operator Binding by Heterologous and Chimeric ArgR Repressors from Escherichia coli and Bacillus stearothermophilus

Por Ghochikyan, Anahit, Miltcheva Karaivanova, Iovka, Lecocq, Michèle, Vusio, Patricia, Arnaud, Marie-Claire, Snapyan, Marina, Weigel, Pierre, Guével, Laetitia, Buckle, Malcolm, Sakanyan, Vehary
Publicado em 2002

Alzheimer's Disease Peptide Epitope Vaccine Reduces Insoluble But Not Soluble/Oligomeric Aβ Species in Amyloid Precursor Protein Transgenic Mice

Por Petrushina, Irina, Ghochikyan, Anahit, Mktrichyan, Mikayel, Mamikonyan, Gregory, Movsesyan, Nina, Davtyan, Hayk, Patel, Archita, Head, Elizabeth, Cribbs, David H., Agadjanyan, Michael G.
Publicado em 2007

Restricted V gene usage and VH/VL pairing of mouse humoral response against the N-terminal immunodominant epitope of the amyloid β peptide

Por Robert, Remy, Lefranc, Marie-Paule, Ghochikyan, Anahit, Agadjanyan, Michael G., Cribbs, David H., Van Nostrand, William E., Wark, Kim L., Dolezal, Olan
Publicado em 2010

A dual vaccine against influenza & Alzheimer’s disease failed to enhance anti-β-amyloid antibody responses in mice with pre-existing virus specific memory

Por Davtyan, Hayk, Ghochikyan, Anahit, Hovakimyan, Armine, Davtyan, Arpine, Cadagan, Richard, Marleau, Annette M., Albrecht, Randy A., García-Sastre, Adolfo, Agadjanyan, Michael G.
Publicado no J Neuroimmunol (2014)

Reducing AD-Like Pathology in 3xTg-AD Mouse Model by DNA Epitope Vaccine — A Novel Immunotherapeutic Strategy

Por Movsesyan, Nina, Ghochikyan, Anahit, Mkrtichyan, Mikayel, Petrushina, Irina, Davtyan, Hayk, Olkhanud, Purevdorj B., Head, Elizabeth, Biragyn, Arya, Cribbs, David H., Agadjanyan, Michael G.
Publicado em 2008

Mannan-Abeta₂₈conjugate prevents Abeta-plaque deposition, but increases microhemorrhages in the brains of vaccinated Tg2576 (APPsw) mice

Por Karapetyan Adrine, Vasilevko Vitaly, Ajdari Rodmehr, Movsesyan Nina, Mamikonyan Grigor, Mkrtichyan Mikayel, Ghochikyan Anahit, Petrushina Irina, Lees Andrew, Agadjanyan Michael G, Cribbs David H
Publicado em 2008-09-01