Comparison of Efficacy of Preventive and Therapeutic Vaccines Targeting the N Terminus of β-Amyloid in an Animal Model of Alzheimer’s Disease

Previously, we reported that Alzheimer’s disease (AD) epitope vaccines (EVs) composed of N-terminal β-amyloid (Aβ(42)) B cell epitope fused with universal foreign T helper (Th) epitope(s) were immunogenic, potent, and safe in different amyloid precursor protein (APP) transgenic mice with early AD-li...

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Bibliografiska uppgifter
I publikationen:Mol Ther
Huvudupphovsmän: Petrushina, Irina, Davtyan, Hayk, Hovakimyan, Armine, Davtyan, Arpine, Passos, Giselle F., Cribbs, David H., Ghochikyan, Anahit, Agadjanyan, Michael G.
Materialtyp: Artigo
Språk:Inglês
Publicerad: American Society of Gene & Cell Therapy 2017
Ämnen:
Original Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC5363310/
https://ncbi.nlm.nih.gov/pubmed/28129111
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ymthe.2016.10.002
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