Refinement of a DNA based Alzheimer disease epitope vaccine in rabbits

We previously demonstrated that our second-generation DNA-based Alzheimer disease (AD) epitope vaccine comprising three copies of a short amyloid-β (Aβ) B cell epitope, Aβ(11) fused with the foreign promiscuous Th epitope, PADRE (p3Aβ(11)-PADRE) was immunogenic in mice. However, since DNA vaccines e...

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Autors principals: Ghochikyan, Anahit, Davtyan, Hayk, Petrushina, Irina, Hovakimyan, Armine, Movsesyan, Nina, Davtyan, Arpine, Kiyatkin, Anatoly, Cribbs, David H., Agadjanyan, Michael G.
Format: Artigo
Idioma:Inglês
Publicat: Landes Bioscience 2013
Matèries:
Research Paper
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3899134/
https://ncbi.nlm.nih.gov/pubmed/23399748
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/hv.23875
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