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Immunogenicity of DNA- and recombinant protein-based Alzheimer Disease epitope vaccines

Alzheimer disease (AD) process involves the accumulation of amyloid plaques and tau tangles in the brain, nevertheless the attempts at targeting the main culprits, neurotoxic β-amyloid (Aβ) peptides, have thus far proven unsuccessful for improving cognitive function. Important lessons about anti-Aβ...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Hum Vaccin Immunother
Hauptverfasser: Davtyan, Hayk, Bacon, Andrew, Petrushina, Irina, Zagorski, Karen, Cribbs, David H, Ghochikyan, Anahit, Agadjanyan, Michael G
Format: Artigo
Sprache:Inglês
Veröffentlicht: Taylor & Francis 2014
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4896595/
https://ncbi.nlm.nih.gov/pubmed/24525778
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/hv.27882
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