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MultiTEP Platform-based DNA Vaccines for alpha-Synucleinopathies: Pre-clinical Evaluation of Immunogenicity and Therapeutic Potency

We have previously demonstrated that anti-Aβ DNA vaccine (AV-1959D) based on our proprietary MultiTEP platform technology is extremely immunogenic in mice, rabbits, and monkeys. Importantly, MultiTEP platform enables development of vaccines targeting pathological molecules involved in various neurod...

תיאור מלא

שמור ב:
מידע ביבליוגרפי
הוצא לאור ב:Neurobiol Aging
Main Authors: Davtyan, Hayk, Zagorski, Karen, Petrushina, Irina, Kazarian, Konstantin, Goldberg, Natalie R.S., Petrosyan, Janet, Blurton-Jones, Mathew, Masliah, Eliezer, Cribbs, David H., Agadjanyan, Michael G., Ghochikyan, Anahit
פורמט: Artigo
שפה:Inglês
יצא לאור: 2017
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC5612893/
https://ncbi.nlm.nih.gov/pubmed/28870518
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neurobiolaging.2017.08.006
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