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Low Concentrations of Anti-Aβ Antibodies Generated in Tg2576 Mice by DNA Epitope Vaccine Fused with 3C3d Molecular Adjuvant Do Not Affect AD Pathology
It has been demonstrated that an active vaccination strategy with protein- or DNA-based epitope vaccines composed of the immunodominant self B cell epitope of amyloid-β(42) (Aβ(42)) and a non-self T helper (Th) cell epitope is an immunotherapeutic approach to preventing or treating Alzheimer's...
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| Main Authors: | , , , , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Mary Ann Liebert, Inc.
2010
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2978548/ https://ncbi.nlm.nih.gov/pubmed/20528468 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/hum.2009.219 |
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