Low Concentrations of Anti-Aβ Antibodies Generated in Tg2576 Mice by DNA Epitope Vaccine Fused with 3C3d Molecular Adjuvant Do Not Affect AD Pathology

It has been demonstrated that an active vaccination strategy with protein- or DNA-based epitope vaccines composed of the immunodominant self B cell epitope of amyloid-β(42) (Aβ(42)) and a non-self T helper (Th) cell epitope is an immunotherapeutic approach to preventing or treating Alzheimer's...

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Detalhes bibliográficos
Main Authors: Movsesyan, Nina, Davtyan, Hayk, Mkrtichyan, Mikayel, Petrushina, Irina, Tiraturyan, Tigran, Ross, Ted, Agadjanyan, Michael G., Ghochikyan, Anahit, Cribbs, David H.
Formato: Artigo
Idioma:Inglês
Publicado em: Mary Ann Liebert, Inc. 2010
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2978548/
https://ncbi.nlm.nih.gov/pubmed/20528468
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/hum.2009.219
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