Cancer-testis antigen, BORIS based vaccine delivered by dendritic cells is extremely effective against a very aggressive and highly metastatic mouse mammary carcinoma

Here, we analyze for the first time the immunological and therapeutic efficacy of a dendritic cell (DC) vaccine based on a cancer-testis antigen, Brother of Regulator of Imprinted Sites (BORIS), an epigenetically acting tumor-promoting transcription factor. Vaccination of mice with DC loaded with tr...

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Detalhes bibliográficos
Main Authors: Mkrtichyan, Mikayel, Ghochikyan, Anahit, Davtyan, Hayk, Movsesyan, Nina, Loukinov, Dmitry, Lobanenkov, Victor, Cribbs, David H., Laust, Amanda K., Nelson, Edward L., Agadjanyan, Michael G.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3156877/
https://ncbi.nlm.nih.gov/pubmed/21641588
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cellimm.2011.05.007
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