Tumor-specific labeling of pancreatic cancer using a humanized anti-CEA antibody conjugated to a near-infrared fluorophore

Por Lwin, Thinzar M., Murakami, Takashi, Miyake, Kentaro, Yazaki, Paul J., Shivley, John E, Hoffman, Robert M., Bouvet, Michael
Publicado no Ann Surg Oncol (2018)

Analysis of stroma labeling during multiple passage of a sarcoma imageable patient-derived orthotopic xenograft (iPDOX) in red fluorescent protein transgenic nude mice

Por Kiyuna, Tasuku, Murakami, Takashi, Tome, Yasunori, Kawaguchi, Kei, Igarashi, Kentaro, Miyake, Kentaro, Kanaya, Fuminori, Singh, Arun, Eilber, Fritz C., Hoffman, Robert M.
Publicado no J Cell Biochem (2017)

Targeting altered cancer methionine metabolism with recombinant methioninase (rMETase) overcomes partial gemcitabine-resistance and regresses a patient-derived orthotopic xenograft...

Por Kawaguchi, Kei, Miyake, Kentaro, Han, Qinghong, Li, Shukuan, Tan, Yuying, Igarashi, Kentaro, Lwin, Thinzar M., Higuchi, Takashi, Kiyuna, Tasuku, Miyake, Masuyo, Oshiro, Hiromichi, Bouvet, Michael, Unno, Michiaki, Hoffman, Robert M.
Publicado no Cell Cycle (2018)

Individualized doxorubicin sensitivity testing of undifferentiated soft tissue sarcoma (USTS) in a patient-derived orthotopic xenograft (PDOX) model demonstrates large differences...

Por Kawaguchi, Kei, Igarashi, Kentaro, Kiyuna, Tasuku, Miyake, Kentaro, Miyake, Masuyo, Murakami, Takashi, Chmielowski, Bartosz, Nelson, Scott D., Russell, Tara A., Dry, Sarah M., Li, Yunfeng, Singh, Arun S., Unno, Michiaki, Eilber, Fritz C., Hoffman, Robert M.
Publicado no Cell Cycle (2018)

Color-coded intravital imaging demonstrates a transforming growth factor-β (TGF-β) antagonist selectively targets stromal cells in a human pancreatic-cancer orthotopic mouse model...

Por Murakami, Takashi, Hiroshima, Yukihiko, Miyake, Kentaro, Hwang, Ho Kyoung, Kiyuna, Tasuku, DeLong, Jonathan C., Lwin, Thinzar M., Matsuyama, Ryusei, Mori, Ryutaro, Kumamoto, Takafumi, Chishima, Takashi, Tanaka, Kuniya, Ichikawa, Yasushi, Bouvet, Michael, Endo, Itaru, Hoffman, Robert M.
Publicado no Cell Cycle (2017)

A patient-derived orthotopic xenograft (PDOX) mouse model of a cisplatinum-resistant osteosarcoma lung metastasis that was sensitive to temozolomide and trabectedin: implications f...

Por Igarashi, Kentaro, Murakami, Takashi, Kawaguchi, Kei, Kiyuna, Tasuku, Miyake, Kentaro, Zhang, Yong, Nelson, Scott D., Dry, Sarah M., Li, Yunfeng, Yanagawa, Jane, Russell, Tara A., Singh, Arun S., Tsuchiya, Hiroyuki, Elliott, Irmina, Eilber, Fritz C., Hoffman, Robert M.
Publicado no Oncotarget (2017)

Combination treatment with recombinant methioninase enables temozolomide to arrest a BRAF V600E melanoma in a patient-derived orthotopic xenograft (PDOX) mouse model

Por Kawaguchi, Kei, Igarashi, Kentaro, Li, Shukuan, Han, Qinghong, Tan, Yuying, Kiyuna, Tasuku, Miyake, Kentaro, Murakami, Takashi, Chmielowski, Bartosz, Nelson, Scott D., Russell, Tara A., Dry, Sarah M., Li, Yunfeng, Unno, Michiaki, Eilber, Fritz C., Hoffman, Robert M.
Publicado no Oncotarget (2017)

A novel anionic-phosphate-platinum complex effectively targets an undifferentiated pleomorphic sarcoma better than cisplatinum and doxorubicin in a patient-derived orthotopic xenog...

Por Igarashi, Kentaro, Kawaguchi, Kei, Murakami, Takashi, Kiyuna, Tasuku, Miyake, Kentaro, Yamamoto, Norio, Hayashi, Katsuhiro, Kimura, Hiroaki, Nelson, Scott D., Dry, Sarah M., Li, Yunfeng, Singh, Arun S., Miwa, Shinji, Odani, Akira, Eilber, Fritz C., Tsuchiya, Hiroyuki, Hoffman, Robert M.
Publicado no Oncotarget (2017)

Recombinant methioninase (rMETase) is an effective therapeutic for BRAF-V600E-negative as well as -positive melanoma in patient-derived orthotopic xenograft (PDOX) mouse models

Por Kawaguchi, Kei, Igarashi, Kentaro, Li, Shukuan, Han, Qinghong, Tan, Yuying, Miyake, Kentaro, Kiyuna, Tasuku, Miyake, Masuyo, Murakami, Takashi, Chmielowski, Bartosz, Nelson, Scott D., Russell, Tara A., Dry, Sarah M., Li, Yunfeng, Unno, Michiaki, Eilber, Fritz C., Hoffman, Robert M.
Publicado no Oncotarget (2017)

Intra-arterial administration of tumor-targeting Salmonella typhimurium A1-R regresses a cisplatin-resistant relapsed osteosarcoma in a patient-derived orthotopic xenograft (PDOX)...

Por Igarashi, Kentaro, Kawaguchi, Kei, Murakami, Takashi, Kiyuna, Tasuku, Miyake, Kentaro, Nelson, Scott D., Dry, Sarah M., Li, Yunfeng, Yanagawa, Jane, Russell, Tara A., Singh, Arun S., Yamamoto, Norio, Hayashi, Katsuhiro, Kimura, Hiroaki, Miwa, Shinji, Tsuchiya, Hiroyuki, Eilber, Fritz C., Hoffman, Robert M.
Publicado no Cell Cycle (2017)

Cervical Cancer Patient-Derived Orthotopic Xenograft (PDOX) Is Sensitive to Cisplatinum and Resistant to Nab-paclitaxel

Por MURAKAMI, TAKASHI, MURATA, TAKUYA, KAWAGUCHI, KEI, KIYUNA, TASUKU, IGARASHI, KENTARO, HWANG, HO KYOUNG, HIROSHIMA, YUKIHIKO, HOZUMI, CHIHIRO, KOMATSU, SHIN, KIKUCHI, TAKASHI, LWIN, THINZAR M., DELONG, JONATHAN C., MIYAKE, KENTARO, ZHANG, YONG, TANAKA, KUNIYA, BOUVET, MICHAEL, ENDO, ITARU, HOFFMAN, ROBERT M.
Publicado no Anticancer Res (2017)

Regorafenib regresses an imatinib-resistant recurrent gastrointestinal stromal tumor (GIST) with a mutation in exons 11 and 17 of c-kit in a patient-derived orthotopic xenograft (P...

Por Miyake, Kentaro, Kawaguchi, Kei, Kiyuna, Tasuku, Miyake, Masuyo, Igarashi, Kentaro, Zhang, Zhiying, Murakami, Takashi, Li, Yunfeng, Nelson, Scott D., Elliott, Irmina, Russell, Tara, Singh, Arun, Hiroshima, Yukihiko, Momiyama, Masashi, Matsuyama, Ryusei, Chishima, Takashi, Endo, Itaru, Eilber, Fritz C., Hoffman, Robert M.
Publicado no Cell Cycle (2018)

Intra-tumor L-methionine level highly correlates with tumor size in both pancreatic cancer and melanoma patient-derived orthotopic xenograft (PDOX) nude-mouse models

Por Kawaguchi, Kei, Han, Qinghong, Li, Shukuan, Tan, Yuying, Igarashi, Kentaro, Miyake, Kentaro, Kiyuna, Tasuku, Miyake, Masuyo, Chemielwski, Bartosz, Nelson, Scott D., Russell, Tara A., Dry, Sarah M., Li, Yunfeng, Singh, Arun S., Eckardt, Mark A., Unno, Michiaki, Eilber, Fritz C., Hoffman, Robert M.
Publicado no Oncotarget (2018)

Targeting methionine with oral recombinant methioninase (o-rMETase) arrests a patient-derived orthotopic xenograft (PDOX) model of BRAF-V600E mutant melanoma: implications for chro...

Por Kawaguchi, Kei, Han, Qinghong, Li, Shukuan, Tan, Yuying, Igarashi, Kentaro, Kiyuna, Tasuku, Miyake, Kentaro, Miyake, Masuyo, Chmielowski, Bartosz, Nelson, Scott D., Russell, Tara A., Dry, Sarah M., Li, Yunfeng, Singh, Arun S., Eckardt, Mark A., Unno, Michiaki, Eilber, Fritz C., Hoffman, Robert M.
Publicado no Cell Cycle (2018)

Temozolomide combined with irinotecan regresses a cisplatinum-resistant relapsed osteosarcoma in a patient-derived orthotopic xenograft (PDOX) precision-oncology mouse model

Por Igarashi, Kentaro, Kawaguchi, Kei, Kiyuna, Tasuku, Miyake, Kentaro, Miyake, Masuyo, Li, Yunfeng, Nelson, Scott D., Dry, Sarah M., Singh, Arun S., Elliott, Irmina A., Russell, Tara A., Eckardt, Mark A., Yamamoto, Norio, Hayashi, Katsuhiro, Kimura, Hiroaki, Miwa, Shinji, Tsuchiya, Hiroyuki, Eilber, Fritz C., Hoffman, Robert M.
Publicado no Oncotarget (2017)

The irony of highly-effective bacterial therapy of a patient-derived orthotopic xenograft (PDOX) model of Ewing's sarcoma, which was blocked by Ewing himself 80 years ago

Por Murakami, Takashi, Kiyuna, Tasuku, Kawaguchi, Kei, Igarashi, Kentaro, Singh, Arun S., Hiroshima, Yukihiko, Zhang, Yong, Zhao, Ming, Miyake, Kentaro, Nelson, Scott D., Dry, Sarah M., Li, Yunfeng, DeLong, Jonathan C., Lwin, Thinzar M., Chishima, Takashi, Tanaka, Kuniya, Bouvet, Michael, Endo, Itaru, Eilber, Fritz C., Hoffman, Robert M.
Publicado no Cell Cycle (2017)

The combination of temozolomide-irinotecan regresses a doxorubicin-resistant patient-derived orthotopic xenograft (PDOX) nude-mouse model of recurrent Ewing’s sarcoma with a FUS-ER...

Por Miyake, Kentaro, Murakami, Takashi, Kiyuna, Tasuku, Igarashi, Kentaro, Kawaguchi, Kei, Miyake, Masuyo, Li, Yunfeng, Nelson, Scott D., Dry, Sarah M., Bouvet, Michael, Elliott, Irmina A., Russell, Tara A., Singh, Arun S., Eckardt, Mark A., Hiroshima, Yukihiko, Momiyama, Masashi, Matsuyama, Ryusei, Chishima, Takashi, Endo, Itaru, Eilber, Fritz C., Hoffman, Robert M.
Publicado no Oncotarget (2017)

Tumor-targeting Salmonella typhimurium A1-R suppressed an imatinib-resistant gastrointestinal stromal tumor with c-kit exon 11 and 17 mutations

Por Miyake, Kentaro, Kawaguchi, Kei, Miyake, Masuyo, Zhao, Ming, Kiyuna, Tasuku, Igarashi, Kentaro, Zhang, Zhiying, Murakami, Takashi, Li, Yunfeng, Nelson, Scott D., Bouvet, Michael, Elliott, Irmina, Russell, Tara A., Singh, Arun S., Hiroshima, Yukihiko, Momiyama, Masashi, Matsuyama, Ryusei, Chishima, Takashi, Singh, Shree Ram, Endo, Itaru, Eilber, Fritz C., Hoffman, Robert M.
Publicado no Heliyon (2018)

Patient-derived orthotopic xenograft models for cancer of unknown primary precisely distinguish chemotherapy, and tumor-targeting S. typhimurium A1-R is superior to first-line chem...

Por Miyake, Kentaro, Kiyuna, Tasuku, Miyake, Masuyo, Kawaguchi, Kei, Yoon, Sang Nam, Zhang, Zhiying, Igarashi, Kentaro, Razmjooei, Sahar, Wangsiricharoen, Sintawat, Murakami, Takashi, Li, Yunfeng, Nelson, Scott D., Russell, Tara A., Singh, Arun S., Hiroshima, Yukihiko, Momiyama, Masashi, Matsuyama, Ryusei, Chishima, Takashi, Singh, Shree Ram, Endo, Itaru, Eilber, Fritz C., Hoffman, Robert M.
Publicado no Signal Transduct Target Ther (2018)

Recombinant methioninase effectively targets a Ewing's sarcoma in a patient-derived orthotopic xenograft (PDOX) nude-mouse model

Por Murakami, Takashi, Li, Shukuan, Han, Qinghong, Tan, Yuying, Kiyuna, Tasuku, Igarashi, Kentaro, Kawaguchi, Kei, Hwang, Ho Kyoung, Miyake, Kentaro, Singh, Arun S., Nelson, Scott D., Dry, Sarah M., Li, Yunfeng, Hiroshima, Yukihiko, Lwin, Thinzar M., DeLong, Jonathan C., Chishima, Takashi, Tanaka, Kuniya, Bouvet, Michael, Endo, Itaru, Eilber, Fritz C., Hoffman, Robert M.
Publicado no Oncotarget (2017)