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Tumor-specific labeling of pancreatic cancer using a humanized anti-CEA antibody conjugated to a near-infrared fluorophore

BACKGROUND/PURPOSE: Development of a humanized fluorophore-conjugated antibody that can improve contrast for fluorescence guided oncologic surgeries. METHODS: BxPC-3-GFP pancreatic cancer cells were injected into flanks of nude mice. Fragments of subcutaneous tumors were grafted onto the pancreatic...

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Dades bibliogràfiques
Publicat a:Ann Surg Oncol
Autors principals: Lwin, Thinzar M., Murakami, Takashi, Miyake, Kentaro, Yazaki, Paul J., Shivley, John E, Hoffman, Robert M., Bouvet, Michael
Format: Artigo
Idioma:Inglês
Publicat: 2018
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5842124/
https://ncbi.nlm.nih.gov/pubmed/29372363
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1245/s10434-018-6344-6
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