Tumor-specific, near-infrared nanobody probe rapidly labels tumors in an orthotopic mouse model of pancreatic cancer

BACKGROUND: Nanobodies, derived from camelid antibodies made of only heavy chains, are the smallest, biologic, antigen-binding fragments (~15kDa) with faster pharmacokinetics and better tumor penetration efficiency than standard antibodies. The present study evaluates the efficacy of a fluorescent,...

Cur síos iomlán

Na minha lista:
Sonraí Bibleagrafaíochta
Foilsithe in:Surgery
Main Authors: Lwin, Thinzar M., Hernot, Sophie, Hollandsworth, Hannah, Amirfakhri, Siamak, Filemoni, Filemoni, Debie, Pieterjan, Hoffman, Robert M., Bouvet, Michael
Formáid: Artigo
Teanga:Inglês
Foilsithe: 2020
Ábhair:
Article
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7311276/
https://ncbi.nlm.nih.gov/pubmed/32370916
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.surg.2020.02.020
Clibeanna: Cuir Clib Leis
Gan Chlibeanna, Bí ar an gcéad duine leis an taifead seo a chlibeáil!

Míreanna Comhchosúla