Anti-Claudin-1 Conjugated to a Near-Infrared Fluorophore Targets Colon Cancer in PDOX Mouse Models

INTRODUCTION: Claudins are tight-junction proteins, which maintain an epithelial barrier in normal colon cells. Overexpression of Claudin-1 has been implicated for development of colon cancer. We postulated that Claudin-1 may be a useful target in near-infrared imaging and fluorescence-guided surger...

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Bibliografske podrobnosti
izdano v:J Surg Res
Main Authors: Hollandsworth, Hannah M., Lwin, Thinzar M., Amirfakhri, Siamak, Filemoni, Filemoni, Batra, Surinder K., Hoffman, Robert M., Dhawan, Punita, Bouvet, Michael
Format: Artigo
Jezik:Inglês
Izdano: 2019
Teme:
Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC7144806/
https://ncbi.nlm.nih.gov/pubmed/31077946
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jss.2019.04.048
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