Tumor-specific, near-infrared nanobody probe rapidly labels tumors in an orthotopic mouse model of pancreatic cancer

BACKGROUND: Nanobodies, derived from camelid antibodies made of only heavy chains, are the smallest, biologic, antigen-binding fragments (~15kDa) with faster pharmacokinetics and better tumor penetration efficiency than standard antibodies. The present study evaluates the efficacy of a fluorescent,...

Celý popis

Uloženo v:
Podrobná bibliografie
Vydáno v:Surgery
Hlavní autoři: Lwin, Thinzar M., Hernot, Sophie, Hollandsworth, Hannah, Amirfakhri, Siamak, Filemoni, Filemoni, Debie, Pieterjan, Hoffman, Robert M., Bouvet, Michael
Médium: Artigo
Jazyk:Inglês
Vydáno: 2020
Témata:
Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7311276/
https://ncbi.nlm.nih.gov/pubmed/32370916
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.surg.2020.02.020
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky