Fluorescent humanized anti-CEA antibody specifically labels metastatic pancreatic cancer in a patient-derived orthotopic xenograft (PDOX) mouse model

Pancreatic cancer is a highly lethal disease in part due to incomplete tumor resection. Targeting by tumor-specific antibodies conjugated with a fluorescent label can result in selective labeling of cancer in vivo for surgical navigation. In the present study, we describe a patient-derived orthotopi...

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Veröffentlicht in:Oncotarget
Hauptverfasser: Lwin, Thinzar M., Miyake, Kentaro, Murakami, Takashi, DeLong, Jonathan C., Amirfakhri, Siamak, Filemoni, Filemoni, Yoon, Sang Nam, Yazaki, Paul J., Shivley, John E., Datnow, Brian, Clary, Bryan M., Hoffman, Robert M., Bouvet, Michael
Format: Artigo
Sprache:Inglês
Veröffentlicht: Impact Journals LLC 2018
Schlagworte:
Research Paper
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6324662/
https://ncbi.nlm.nih.gov/pubmed/30647873
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.26484
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