Disintegrin targeting of an α(v)β(3) integrin-over-expressing high-metastatic human osteosarcoma with echistatin inhibits cell proliferation, migration, invasion and adhesion in vi...

Por Tome, Yasunori, Kimura, Hiroaki, Kiyuna, Tasuku, Sugimoto, Naotoshi, Tsuchiya, Hiroyuki, Kanaya, Fuminori, Bouvet, Michael, Hoffman, Robert M.
Publicado no Oncotarget (2016)

Analysis of stroma labeling during multiple passage of a sarcoma imageable patient-derived orthotopic xenograft (iPDOX) in red fluorescent protein transgenic nude mice

Por Kiyuna, Tasuku, Murakami, Takashi, Tome, Yasunori, Kawaguchi, Kei, Igarashi, Kentaro, Miyake, Kentaro, Kanaya, Fuminori, Singh, Arun, Eilber, Fritz C., Hoffman, Robert M.
Publicado no J Cell Biochem (2017)

High-efficacy targeting of colon-cancer liver metastasis with Salmonella typhimurium A1-R via intra-portal-vein injection in orthotopic nude-mouse models

Por Kawaguchi, Kei, Murakami, Takashi, Suetsugu, Atsushi, Kiyuna, Tasuku, Igarashi, Kentaro, Hiroshima, Yukihiko, Zhao, Ming, Zhang, Yong, Bouvet, Michael, Clary, Bryan M., Unno, Michiaki, Hoffman, Robert M.
Publicado no Oncotarget (2016)

MEK inhibitors cobimetinib and trametinib, regressed a gemcitabine-resistant pancreatic-cancer patient-derived orthotopic xenograft (PDOX)

Por Kawaguchi, Kei, Igarashi, Kentaro, Murakami, Takashi, Kiyuna, Tasuku, Lwin, Thinzar M., Hwang, Ho Kyoung, Delong, Jonathan C., Clary, Bryan M., Bouvet, Michael, Unno, Michiaki, Hoffman, Robert M.
Publicado no Oncotarget (2017)

Vemurafenib-resistant BRAF-V600E-mutated melanoma is regressed by MEK-targeting drug trametinib, but not cobimetinib in a patient-derived orthotopic xenograft (PDOX) mouse model

Por Kawaguchi, Kei, Murakami, Takashi, Chmielowski, Bartosz, Igarashi, Kentaro, Kiyuna, Tasuku, Unno, Michiaki, Nelson, Scott D., Russell, Tara A., Dry, Sarah M., Li, Yunfeng, Eilber, Fritz C., Hoffman, Robert M.
Publicado no Oncotarget (2016)

High efficacy of tumor-targeting Salmonella typhimurium A1-R on a doxorubicin- and dactolisib-resistant follicular dendritic-cell sarcoma in a patient-derived orthotopic xenograft...

Por Kiyuna, Tasuku, Murakami, Takashi, Tome, Yasunori, Kawaguchi, Kei, Igarashi, Kentaro, Zhang, Yong, Zhao, Ming, Li, Yunfeng, Bouvet, Michael, Kanaya, Fuminori, Singh, Arun, Dry, Sarah, Eilber, Fritz C., Hoffman, Robert M.
Publicado no Oncotarget (2016)

Combination of gemcitabine and docetaxel regresses both gastric leiomyosarcoma proliferation and invasion in an imageable patient-derived orthotopic xenograft (iPDOX) model

Por Kawaguchi, Kei, Igarashi, Kentaro, Murakami, Takashi, Kiyuna, Tasuku, Nelson, Scott D., Dry, Sarah M., Li, Yunfeng, Russell, Tara A., Singh, Arun S., Chmielowski, Bartosz, Unno, Michiaki, Eilber, Fritz C., Hoffman, Robert M.
Publicado no Cell Cycle (2017)

Patient-derived orthotopic xenograft (PDOX) mouse model of adult rhabdomyosarcoma invades and recurs after resection in contrast to the subcutaneous ectopic model

Por Igarashi, Kentaro, Kawaguchi, Kei, Kiyuna, Tasuku, Murakami, Takashi, Miwa, Shinji, Nelson, Scott D., Dry, Sarah M., Li, Yunfeng, Singh, Arun, Kimura, Hiroaki, Hayashi, Katsuhiro, Yamamoto, Norio, Tsuchiya, Hiroyuki, Eilber, Fritz C., Hoffman, Robert M.
Publicado no Cell Cycle (2016)

Temozolomide combined with irinotecan caused regression in an adult pleomorphic rhabdomyosarcoma patient-derived orthotopic xenograft (PDOX) nude-mouse model

Por Igarashi, Kentaro, Kawaguchi, Kei, Kiyuna, Tasuku, Murakami, Takashi, Miwa, Shinji, Nelson, Scott D., Dry, Sarah M., Li, Yunfeng, Singh, Arun S., Kimura, Hiroaki, Hayashi, Katsuhiro, Yamamoto, Norio, Tsuchiya, Hiroyuki, Eilber, Fritz C., Hoffman, Robert M.
Publicado no Oncotarget (2017)

Tumor-targeting Salmonella typhimurium A1-R combined with temozolomide regresses malignant melanoma with a BRAF-V600E mutation in a patient-derived orthotopic xenograft (PDOX) mode...

Por Kawaguchi, Kei, Igarashi, Kentaro, Murakami, Takashi, Chmielowski, Bartosz, Kiyuna, Tasuku, Zhao, Ming, Zhang, Yong, Singh, Arun, Unno, Michiaki, Nelson, Scott D., Russell, Tara A., Dry, Sarah M., Li, Yunfeng, Eilber, Fritz C., Hoffman, Robert M.
Publicado no Oncotarget (2016)

Salmonella typhimurium A1-R targeting of a chemotherapy-resistant BRAF-V600E melanoma in a patient-derived orthotopic xenograft (PDOX) model is enhanced in combination with either...

Por Kawaguchi, Kei, Igarashi, Kentaro, Murakami, Takashi, Kiyuna, Tasuku, Zhao, Ming, Zhang, Yong, Nelson, Scott D., Russell, Tara A., Dry, Sarah M., Singh, Arun S., Chmielowski, Bartosz, Li, Yunfeng, Unno, Michiaki, Eilber, Fritz C., Hoffman, Robert M.
Publicado no Cell Cycle (2017)

Toxicology and efficacy of tumor-targeting Salmonella typhimurium A1-R compared to VNP 20009 in a syngeneic mouse tumor model in immunocompetent mice

Por Zhang, Yong, Cao, Wenluo, Toneri, Makoto, Zhang, Nan, Kiyuna, Tasuku, Murakami, Takashi, Nelson, Scott D., Dry, Sarah M., Li, Yunfeng, Li, Shukuan, Wang, Xiaoen, Ma, Huaiyu, Singh, Arun S., Eilber, Fritz C., Hoffman, Robert M., Zhao, Ming
Publicado no Oncotarget (2017)

Color-coded intravital imaging demonstrates a transforming growth factor-β (TGF-β) antagonist selectively targets stromal cells in a human pancreatic-cancer orthotopic mouse model...

Por Murakami, Takashi, Hiroshima, Yukihiko, Miyake, Kentaro, Hwang, Ho Kyoung, Kiyuna, Tasuku, DeLong, Jonathan C., Lwin, Thinzar M., Matsuyama, Ryusei, Mori, Ryutaro, Kumamoto, Takafumi, Chishima, Takashi, Tanaka, Kuniya, Ichikawa, Yasushi, Bouvet, Michael, Endo, Itaru, Hoffman, Robert M.
Publicado no Cell Cycle (2017)

A patient-derived orthotopic xenograft (PDOX) mouse model of a cisplatinum-resistant osteosarcoma lung metastasis that was sensitive to temozolomide and trabectedin: implications f...

Por Igarashi, Kentaro, Murakami, Takashi, Kawaguchi, Kei, Kiyuna, Tasuku, Miyake, Kentaro, Zhang, Yong, Nelson, Scott D., Dry, Sarah M., Li, Yunfeng, Yanagawa, Jane, Russell, Tara A., Singh, Arun S., Tsuchiya, Hiroyuki, Elliott, Irmina, Eilber, Fritz C., Hoffman, Robert M.
Publicado no Oncotarget (2017)

A novel anionic-phosphate-platinum complex effectively targets an undifferentiated pleomorphic sarcoma better than cisplatinum and doxorubicin in a patient-derived orthotopic xenog...

Por Igarashi, Kentaro, Kawaguchi, Kei, Murakami, Takashi, Kiyuna, Tasuku, Miyake, Kentaro, Yamamoto, Norio, Hayashi, Katsuhiro, Kimura, Hiroaki, Nelson, Scott D., Dry, Sarah M., Li, Yunfeng, Singh, Arun S., Miwa, Shinji, Odani, Akira, Eilber, Fritz C., Tsuchiya, Hiroyuki, Hoffman, Robert M.
Publicado no Oncotarget (2017)

Intra-arterial administration of tumor-targeting Salmonella typhimurium A1-R regresses a cisplatin-resistant relapsed osteosarcoma in a patient-derived orthotopic xenograft (PDOX)...

Por Igarashi, Kentaro, Kawaguchi, Kei, Murakami, Takashi, Kiyuna, Tasuku, Miyake, Kentaro, Nelson, Scott D., Dry, Sarah M., Li, Yunfeng, Yanagawa, Jane, Russell, Tara A., Singh, Arun S., Yamamoto, Norio, Hayashi, Katsuhiro, Kimura, Hiroaki, Miwa, Shinji, Tsuchiya, Hiroyuki, Eilber, Fritz C., Hoffman, Robert M.
Publicado no Cell Cycle (2017)

Tumor-targeting Salmonella typhimurium A1-R regresses an osteosarcoma in a patient-derived xenograft model resistant to a molecular-targeting drug

Por Murakami, Takashi, Igarashi, Kentaro, Kawaguchi, Kei, Kiyuna, Tasuku, Zhang, Yong, Zhao, Ming, Hiroshima, Yukihiko, Nelson, Scott D., Dry, Sarah M., Li, Yunfeng, Yanagawa, Jane, Russell, Tara, Federman, Noah, Singh, Arun, Elliott, Irmina, Matsuyama, Ryusei, Chishima, Takashi, Tanaka, Kuniya, Endo, Itaru, Eilber, Fritz C., Hoffman, Robert M.
Publicado no Oncotarget (2016)

The irony of highly-effective bacterial therapy of a patient-derived orthotopic xenograft (PDOX) model of Ewing's sarcoma, which was blocked by Ewing himself 80 years ago

Por Murakami, Takashi, Kiyuna, Tasuku, Kawaguchi, Kei, Igarashi, Kentaro, Singh, Arun S., Hiroshima, Yukihiko, Zhang, Yong, Zhao, Ming, Miyake, Kentaro, Nelson, Scott D., Dry, Sarah M., Li, Yunfeng, DeLong, Jonathan C., Lwin, Thinzar M., Chishima, Takashi, Tanaka, Kuniya, Bouvet, Michael, Endo, Itaru, Eilber, Fritz C., Hoffman, Robert M.
Publicado no Cell Cycle (2017)

Effective molecular targeting of CDK4/6 and IGF-1R in a rare FUS-ERG fusion CDKN2A-deletion doxorubicin-resistant Ewing's sarcoma patient-derived orthotopic xenograft (PDOX) nude-m...

Por Murakami, Takashi, Singh, Arun S., Kiyuna, Tasuku, Dry, Sarah M., Li, Yunfeng, James, Aaron W., Igarashi, Kentaro, Kawaguchi, Kei, DeLong, Jonathan C., Zhang, Yong, Hiroshima, Yukihiko, Russell, Tara, Eckardt, Mark A., Yanagawa, Jane, Federman, Noah, Matsuyama, Ryusei, Chishima, Takashi, Tanaka, Kuniya, Bouvet, Michael, Endo, Itaru, Eilber, Fritz C., Hoffman, Robert M.
Publicado no Oncotarget (2016)

Recombinant methioninase effectively targets a Ewing's sarcoma in a patient-derived orthotopic xenograft (PDOX) nude-mouse model

Por Murakami, Takashi, Li, Shukuan, Han, Qinghong, Tan, Yuying, Kiyuna, Tasuku, Igarashi, Kentaro, Kawaguchi, Kei, Hwang, Ho Kyoung, Miyake, Kentaro, Singh, Arun S., Nelson, Scott D., Dry, Sarah M., Li, Yunfeng, Hiroshima, Yukihiko, Lwin, Thinzar M., DeLong, Jonathan C., Chishima, Takashi, Tanaka, Kuniya, Bouvet, Michael, Endo, Itaru, Eilber, Fritz C., Hoffman, Robert M.
Publicado no Oncotarget (2017)