Tumor-targeting Salmonella typhimurium A1-R combined with temozolomide regresses malignant melanoma with a BRAF-V600E mutation in a patient-derived orthotopic xenograft (PDOX) model

Melanoma is a recalcitrant disease in need of transformative therapuetics. The present study used a patient-derived orthotopic xenograft (PDOX) nude-mouse model of melanoma with a BRAF-V600E mutation to determine the efficacy of temozolomide (TEM) combined with tumor-targeting Salmonella typhimurium...

Descripció completa

Guardat en:
Dades bibliogràfiques
Publicat a:Oncotarget
Autors principals: Kawaguchi, Kei, Igarashi, Kentaro, Murakami, Takashi, Chmielowski, Bartosz, Kiyuna, Tasuku, Zhao, Ming, Zhang, Yong, Singh, Arun, Unno, Michiaki, Nelson, Scott D., Russell, Tara A., Dry, Sarah M., Li, Yunfeng, Eilber, Fritz C., Hoffman, Robert M.
Format: Artigo
Idioma:Inglês
Publicat: Impact Journals LLC 2016
Matèries:
Research Paper
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5349886/
https://ncbi.nlm.nih.gov/pubmed/27835903
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.13231
Etiquetes: Afegir etiqueta
Sense etiquetes, Sigues el primer a etiquetar aquest registre!

Ítems similars