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Disintegrin targeting of an α(v)β(3) integrin-over-expressing high-metastatic human osteosarcoma with echistatin inhibits cell proliferation, migration, invasion and adhesion in vitro
The in vitro efficacy of the disintegrin echistatin was tested on a high-metastatic variant of 143B human osteosarcoma, 143B-LM4, which over-expresses α(v)β(3) integrin. Echistatin is an RGD cyclic peptide and an antagonist of α(v)β(3) integrin. In the present study, echistatin inhibited cell prolif...
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| Publicado no: | Oncotarget |
|---|---|
| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Impact Journals LLC
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5216800/ https://ncbi.nlm.nih.gov/pubmed/27331872 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.10111 |
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