High efficacy of tumor-targeting Salmonella typhimurium A1-R on a doxorubicin- and dactolisib-resistant follicular dendritic-cell sarcoma in a patient-derived orthotopic xenograft PDOX nude mouse model

Follicular dendritic-cell sarcoma (FDCS) is a rare and recalcitrant disease. In the present study, a patient-derived orthotopic xenograft (PDOX) mouse model of FDCS was established in the biceps muscle of nude mice. The FDCS PDOX was resistant to both doxorubicin (DOX) and NVP-BEZ235, dactolisib (BE...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Kiyuna, Tasuku, Murakami, Takashi, Tome, Yasunori, Kawaguchi, Kei, Igarashi, Kentaro, Zhang, Yong, Zhao, Ming, Li, Yunfeng, Bouvet, Michael, Kanaya, Fuminori, Singh, Arun, Dry, Sarah, Eilber, Fritz C., Hoffman, Robert M.
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2016
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5078074/
https://ncbi.nlm.nih.gov/pubmed/27105519
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.8848
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