Temozolomide combined with irinotecan regresses a cisplatinum-resistant relapsed osteosarcoma in a patient-derived orthotopic xenograft (PDOX) precision-oncology mouse model

Relapsed osteosarcoma is a recalcitrant tumor. A patient's cisplatinum (CDDP)-resistant relapsed osteosarcoma lung metastasis was previously established orthotopically in the distal femur of mice to establish a patient-derived orthotopic xenograft (PDOX) model. In the present study, the PDOX mo...

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Bibliografski detalji
Izdano u:Oncotarget
Glavni autori: Igarashi, Kentaro, Kawaguchi, Kei, Kiyuna, Tasuku, Miyake, Kentaro, Miyake, Masuyo, Li, Yunfeng, Nelson, Scott D., Dry, Sarah M., Singh, Arun S., Elliott, Irmina A., Russell, Tara A., Eckardt, Mark A., Yamamoto, Norio, Hayashi, Katsuhiro, Kimura, Hiroaki, Miwa, Shinji, Tsuchiya, Hiroyuki, Eilber, Fritz C., Hoffman, Robert M.
Format: Artigo
Jezik:Inglês
Izdano: Impact Journals LLC 2017
Teme:
Research Paper
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5814257/
https://ncbi.nlm.nih.gov/pubmed/29487690
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.22892
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