Avoidance of stimulation improves engraftment of cultured and retrovirally transduced hematopoietic cells in primates

le Takatoku, Masaaki, Sellers, Stephanie, Agricola, Brian A., Metzger, Mark E., Kato, Ikunoshin, Donahue, Robert E., Dunbar, Cynthia E.
Foilsithe 2001

Busulfan pharmacokinetics, toxicity, and low-dose conditioning for autologous transplantation of genetically modified hematopoietic stem cells in the rhesus macaque model

le Kang, Elizabeth M., Hsieh, Matthew M., Metzger, Mark, Krouse, Allen, Donahue, Robert E., Sadelain, Michel, Tisdale, John F.
Foilsithe 2006

Plerixafor (AMD3100) and granulocyte colony-stimulating factor (G-CSF) mobilize different CD34(+) cell populations based on global gene and microRNA expression signatures

le Donahue, Robert E., Jin, Ping, Bonifacino, Aylin C., Metzger, Mark E., Ren, Jiaqiang, Wang, Ena, Stroncek, David F.
Foilsithe 2009

Sorting of Transgenic Secretory Proteins in Rhesus Macaque Parotid Glands After Adenovirus-Mediated Gene Transfer

le Voutetakis, Antonis, Zheng, Changyu, Metzger, Mark, Cotrim, Ana P., Donahue, Robert E., Dunbar, Cynthia E., Baum, Bruce J.
Foilsithe 2008

AMD3100 mobilizes hematopoietic stem cells with long-term repopulating capacity in nonhuman primates

le Larochelle, André, Krouse, Allen, Metzger, Mark, Orlic, Donald, Donahue, Robert E., Fricker, Simon, Bridger, Gary, Dunbar, Cynthia E., Hematti, Peiman
Foilsithe 2006

Marking and Gene Expression by a Lentivirus Vector in Transplanted Human and Nonhuman Primate CD34(+) Cells

le An, Dong Sung, Wersto, Robert P., Agricola, Brian A., Metzger, Mark E., Lu, Stephanie, Amado, Rafael G., Chen, Irvin S. Y., Donahue, Robert E.
Foilsithe 2000

Bone Marrow as a Hematopoietic Stem Cell Source for Gene Therapy in Sickle Cell Disease: Evidence from Rhesus and SCD Patients

le Uchida, Naoya, Fujita, Atsushi, Hsieh, Matthew M., Bonifacino, Aylin C., Krouse, Allen E., Metzger, Mark E., Donahue, Robert E., Tisdale, John F.
Foilsithe in Hum Gene Ther Clin Dev (2017)

Transient Neutropenia Following Granulocyte-Colony Stimulating Factor Administration is Associated with Neutrophil Accumulation in Pulmonary Vasculature

le DeJesus, Catherine E., Egen, Jackson, Metzger, Mark, Alvarez, Xavier, Combs, Christian A., Malide, Daniela, Yu, Zu Xi, Tian, Xin, Donahue, Robert E.
Foilsithe 2010

Thymidine Kinase Suicide Gene-mediated Ganciclovir Ablation of Autologous Gene-modified Rhesus Hematopoiesis

le Barese, Cecilia N, Krouse, Allen E, Metzger, Mark E, King, Connor A, Traversari, Catia, Marini, Frank C, Donahue, Robert E, Dunbar, Cynthia E
Foilsithe 2012

Peripheral blood stem cell transplants do not result in endometrial stromal engraftment

le Wolff, Erin F., Uchida, Naoya, Donahue, Robert E., Metzger, Mark E., Hsieh, Matthew M., Libfraind, Lauren L., Hill, Micah J., Tisdale, John F.
Foilsithe 2012

Paradoxical Drop in Circulating Neutrophil Count Following Granulocyte-Colony Stimulating Factor and Stem Cell Factor Administration in Rhesus Macaques: Rapid Neutrophil Decline Fo...

le Gordon, Brent C., Revenis, Amy M., Bonifacino, Aylin C., Sander, William E., Metzger, Mark E., Krouse, Allen E., Usherson, Tatiana N., Donahue., Robert E.
Foilsithe 2007

Development of a Human Immunodeficiency Virus Type 1-Based Lentiviral Vector That Allows Efficient Transduction of both Human and Rhesus Blood Cells

le Uchida, Naoya, Washington, Kareem N., Hayakawa, Jun, Hsieh, Matthew M., Bonifacino, Aylin C., Krouse, Allen E., Metzger, Mark E., Donahue, Robert E., Tisdale, John F.
Foilsithe 2009

Transient In Vivo β-Globin Production After Lentiviral Gene Transfer to Hematopoietic Stem Cells in the Nonhuman Primate

le Hayakawa, Jun, Ueda, Takahiro, Lisowski, Leszek, Hsieh, Matthew M., Washington, Kareem, Phang, Oswald, Metzger, Mark, Krouse, Allen, Donahue, Robert E., Sadelain, Michel, Tisdale, John F.
Foilsithe 2009

Lentivirus Vector-Mediated Hematopoietic Stem Cell Gene Transfer of Common Gamma-Chain Cytokine Receptor in Rhesus Macaques

le An, Dong Sung, Kung, Sam K. P., Bonifacino, Aylin, Wersto, Robert P., Metzger, Mark E., Agricola, Brian A., Mao, Si Hua, Chen, Irvin S. Y., Donahue, Robert E.
Foilsithe 2001

Total body irradiation must be delivered at high dose for efficient engraftment and tolerance in a rhesus stem cell gene therapy model

le Uchida, Naoya, Weitzel, R Patrick, Shvygin, Anna, Skala, Luke P, Raines, Lydia, Bonifacino, Aylin C, Krouse, Allen E, Metzger, Mark E, Donahue, Robert E, Tisdale, John F
Foilsithe in Mol Ther Methods Clin Dev (2016)

In Vitro Culture During Retroviral Transduction Improves Thymic Repopulation and Output After Total Body Irradiation and Autologous Peripheral Blood Progenitor Cell Transplantation...

le Loré, Karin, Seggewiss, Ruth, Guenaga, F. Javier, Pittaluga, Stefania, Donahue, Robert E., Krouse, Allen, Metzger, Mark E., Koup, Richard A., Reilly, Cavan, Douek, Daniel C., Dunbar, Cynthia E.
Foilsithe 2006

Significant mobilization of both conventional and regulatory T cells with AMD3100

le Kean, Leslie S., Sen, Sharon, Onabajo, Olusegun, Singh, Karnail, Robertson, Jennifer, Stempora, Linda, Bonifacino, Aylin C., Metzger, Mark E., Promislow, Daniel E. L., Mattapallil, Joseph J., Donahue, Robert E.
Foilsithe 2011

Development of a forward-oriented therapeutic lentiviral vector for hemoglobin disorders

le Uchida, Naoya, Hsieh, Matthew M., Raines, Lydia, Haro-Mora, Juan J., Demirci, Selami, Bonifacino, Aylin C., Krouse, Allen E., Metzger, Mark E., Donahue, Robert E., Tisdale, John F.
Foilsithe in Nat Commun (2019)

Integration-specific In Vitro Evaluation of Lentivirally Transduced Rhesus CD34(+) Cells Correlates With In Vivo Vector Copy Number

le Uchida, Naoya, Evans, Molly E, Hsieh, Matthew M, Bonifacino, Aylin C, Krouse, Allen E, Metzger, Mark E, Sellers, Stephanie E, Dunbar, Cynthia E, Donahue, Robert E, Tisdale, John F
Foilsithe 2013

Regulated Apoptosis of Genetically-Modified Hematopoietic Stem and Progenitor Cells via an Inducible Caspase-9 Suicide Gene in Rhesus Macaques

le Barese, Cecilia N., Felizardo, Tania C., Sellers, Stephanie E., Keyvanfar, Keyvan, Di Stasi, Antonio, Metzger, Mark E., Krouse, Allen E., Donahue, Robert E., Spencer, David M., Dunbar, Cynthia E.
Foilsithe in Stem Cells (2015)