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Busulfan pharmacokinetics, toxicity, and low-dose conditioning for autologous transplantation of genetically modified hematopoietic stem cells in the rhesus macaque model

OBJECTIVE: Gene transfer to hematopoietic stem cells has recently been demonstrated to benefit a small number of patients in whom a selective advantage is conferred upon genetically modified cells; however, in disorders where no such selective advantage is conferred, conditioning appears necessary t...

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Detalhes bibliográficos
Main Authors: Kang, Elizabeth M., Hsieh, Matthew M., Metzger, Mark, Krouse, Allen, Donahue, Robert E., Sadelain, Michel, Tisdale, John F.
Formato: Artigo
Idioma:Inglês
Publicado em: 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2676898/
https://ncbi.nlm.nih.gov/pubmed/16459181
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.exphem.2005.10.010
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