Transient In Vivo β-Globin Production After Lentiviral Gene Transfer to Hematopoietic Stem Cells in the Nonhuman Primate

Inherited disorders of globin synthesis remain desirable targets for hematopoietic stem cell (HSC)-based therapies. Gene transfer using retroviral vectors offers an alternative to allogeneic HSC transplantation by the permanent integration of potentially therapeutic genes into primary autologous HSC...

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Detalhes bibliográficos
Main Authors: Hayakawa, Jun, Ueda, Takahiro, Lisowski, Leszek, Hsieh, Matthew M., Washington, Kareem, Phang, Oswald, Metzger, Mark, Krouse, Allen, Donahue, Robert E., Sadelain, Michel, Tisdale, John F.
Formato: Artigo
Idioma:Inglês
Publicado em: Mary Ann Liebert, Inc. 2009
Assuntos:
Scientific Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2828625/
https://ncbi.nlm.nih.gov/pubmed/19222366
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/hum.2008.186
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